Ownership Submission
FORM 3
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  Braeburn Pharmaceuticals BVBA SPRL
2. Date of Event Requiring Statement (Month/Day/Year)
11/25/2013
3. Issuer Name and Ticker or Trading Symbol
TITAN PHARMACEUTICALS INC [TTNP]
(Last)
(First)
(Middle)
BRUGMANNLAAN 147
4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

VORST, C9 1190
6. Individual or Joint/Group Filing(Check Applicable Line)
___ Form filed by One Reporting Person
_X_ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)
2. Amount of Securities Beneficially Owned
(Instr. 4)
3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)
4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock 9,650,000
D (1)
 

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)
2. Date Exercisable and Expiration Date
(Month/Day/Year)
3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)
4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)
6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
Braeburn Pharmaceuticals BVBA SPRL
BRUGMANNLAAN 147
VORST, C9 1190
    X    
Apple Tree Consolidated BVBA SPRL
BRUGMANNLAAN 147
VORST, C9 1190
    X    
Apple Tree Investments S.a.r.l
1 BOULEVARD DE LA FOIRE
N4 L-1528
    X    
Apple Tree Partners IV, L.P.
47 HULFISH STREET, SUITE 441
PRINCETON, NJ 08542
    X    
ATP III GP, Ltd.
47 HULFISH STREET, SUITE 441
PRINCETON, NJ 08542
    X    
Harrison Seth Loring
47 HULFISH STREET, SUITE 441
PRINCETON, NJ 08542
    X    

Signatures

/s/ Lauren Farrell, as attorney-in-fact for Seth L. Harrison, Manager of Braeburn Pharmaceuticals BVBA SPRL 12/04/2013
**Signature of Reporting Person Date

/s/ Lauren Farrell, as attorney-in-fact for Seth L. Harrison, Manager of Apple Tree Consolidated BVBA SPRL 12/04/2013
**Signature of Reporting Person Date

/s/ Lauren Farrell, as attorney-in-fact for Seth L. Harrison, Manager of Apple Tree Investments S.a.r.l 12/04/2013
**Signature of Reporting Person Date

/s/ Lauren Farrell, as attorney-in-fact for Seth L. Harrison, Manager of Braeburn Pharmaceuticals BVBA SPRL 12/04/2013
**Signature of Reporting Person Date

/s/ Lauren Farrell, as attorney-in-fact for Seth L. Harrison, Director of ATP III GP, Ltd, general partner of Apple Tree Partners IV, L.P. 12/04/2013
**Signature of Reporting Person Date

/s/ Lauren Farrell, as attorney-in-fact for Seth L. Harrison, Director of ATP III GP, Ltd. 12/04/2013
**Signature of Reporting Person Date

/s/ Lauren Farrell, as attorney-in-fact for Seth L. Harrison 12/04/2013
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Braeburn Pharmaceuticals BVBA SPRL ("Braeburn") is the record owner of the Shares. As the sole owner of Braeburn, Apple Tree Consolidated BVBA SPRL ("ATC") may be deemed to own beneficially the Shares. As the sole owner of ATC, Apple Tree Investments S.a.r.l ("ATI") may be deemed to own beneficially the Shares. As the sole owner of ATI, Apple Tree Partners IV, L.P. ("ATP IV") may be deemed to own beneficially the Shares. As the sole general partner of ATP IV, ATP III GP, Ltd. ("ATP GP") may be deemed to own beneficially the Shares. As the sole owner and director of ATP GP, Seth L. Harrison may be deemed to own beneficially the Shares. Each of the Reporting Persons, except Braeburn, disclaims beneficial ownership of the Shares except to the extent of their pecuniary interest therein, if any.

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