UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

OMB APPROVAL

 

OMB Number:    3235-0578
Expires:    February 28, 2006
Estimated average burden hours per response........20.00

 

 

 

 

FORM N-Q

 

 

QUARTERLY SCHEDULE OF PORTFOLIO HOLDINGS OF REGISTERED
MANAGEMENT INVESTMENT COMPANY

 

Investment Company Act file number

811-06565

 

 

H&Q Healthcare Investors

(Exact name of registrant as specified in charter)

 

30 Rowes Wharf, Boston, MA

 

02110

(Address of principal executive offices)

 

(Zip code)

 

 

(Name and address of agent for service)

 

Copy to:

 

 

Registrant's telephone number, including area code:

 617-772-8500

 

 

Date of fiscal year end:

 September 30

 

 

 

 

Date of reporting period:

 6/30/05

 

 

Form N-Q is to be used by management investment companies, other than small business investment companies registered on Form N-% (ss.ss. 239.24 and 274.5 of this chapter), to file reports with the Commission, not later than 60 days after the close of the first and third fiscal quarters, pursuant to rule 30b-15 under the Investment Company Act of 1940 (17CFR 270.3b1-5).  The Commission may use the information provided on Form N-Q in its regulatory, disclosure review, inspection, and policymaking roles.

 

A registrant is required to disclose the information specified by Form N-Q, and the Commission will make this information public.  A registrant is not required to respond to the collection of information contained in Form N-Q unless the Form displays a currently valid Office of Management and Budget (“OMB”) control number.  Please direct comments concerning the accuracy of the information collection burden estimate and any suggestions for reducing the burden to the Secretary, Securities and Exchange Commission, 450 Fifth Street, NW, Washington, DC 20549-0609.  The OMB has reviewed this collection of information under the clearance requirements of 44 U.S.C. ss.3507.

 



 

Item 1. Schedule of Investments.

 

H&Q HEALTHCARE INVESTORS
SCHEDULE OF INVESTMENTS

JUNE 30, 2005
(Unaudited)

 

SHARES

 

 

 

VALUE

 

 

 

CONVERTIBLE SECURITIES – 12.2% of Net Assets

 

 

 

 

 

Convertible Preferred (Restricted) – 12.0%

 

 

 

 

 

Drug Discovery Technologies – 1.6%

 

 

 

2,380,953

 

Agilix Corporation Series B (a) (b)

 

$

571,429

 

850,436

 

Avalon Pharmaceuticals Series B (a)

 

1,020,523

 

375,000

 

Ceres, Inc. Series C (a)

 

2,250,000

 

27,443

 

Ceres, Inc. Series C-1 (a) (c)

 

164,658

 

277,967

 

Ceres, Inc. Series D (a) (c)

 

1,667,802

 

1,398,732

 

Galileo Pharmaceuticals, Inc. Series F-1 (a)

 

489,556

 

300,000

 

Zyomix, Inc. Series A New (a)

 

30,000

 

300

 

Zyomix, Inc. Series B New (a)

 

30

 

 

 

Emerging Biopharmaceuticals – 3.7%

 

 

 

952,381

 

Agensys, Inc. Series C (a)

 

3,000,000

 

2,586,207

 

Corus Pharma, Inc. Series C (a)

 

3,000,000

 

1,818,182

 

Raven biotechnologies, Inc. Series B (a) (b)

 

1,509,091

 

2,809,157

 

Raven biotechnologies, Inc. Series C (a) (b)

 

2,331,600

 

3,647,417

 

Raven biotechnologies, Inc. Series D (a) (b)

 

1,200,000

 

47,407

 

Therion Biologics Corporation Series A (a)

 

57,837

 

240,000

 

Therion Biologics Corporation Series B (a)

 

292,800

 

407,712

 

Therion Biologics Corporation Series C (a) (c)

 

497,409

 

33,332

 

Therion Biologics Corporation Series C-2 (a) (c)

 

40,665

 

36,092

 

Therion Biologics Corporation Sinking Fund (a)

 

361

 

2,100,000

 

Xanthus Life Sciences, Inc. Series B (a) (b)

 

2,100,000

 

 

 

Healthcare Services – 3.6%

 

 

 

1,577,144

 

CardioNet, Inc. Series C (a) (b)

 

5,520,004

 

484,829

 

CytoLogix Corporation Series A (a) (b)

 

399,984

 

227,130

 

CytoLogix Corporation Series B (a) (b) (c)

 

187,382

 

160,000

 

I-trax, Inc. Series A (a)

 

2,624,000

 

5,384,615

 

PHT Corporation Series D (a) (b)

 

4,200,000

 

1,204,495

 

PHT Corporation Series E (a) (b)

 

939,506

 

 

 

Medical Devices and Diagnostics – 3.1%

 

 

 

4,852,940

 

Concentric Medical, Inc. Series B (a) (b) (d)

 

4,173,528

 

1,744,186

 

Concentric Medical, Inc. Series C (a) (b)

 

1,500,000

 

222,222

 

EPR, Inc. Series A (a)

 

2,222

 

160,000

 

Masimo Corporation Series D (a)

 

1,760,000

 

1,632,653

 

OmniSonics Medical Technologies, Inc. Series B (a) (b)

 

2,181,224

 

1,547,988

 

OmniSonics Medical Technologies, Inc. Series C (a) (b)

 

1,800,000

 

652,173

 

TherOx, Inc. Series H (a)

 

247,826

 

 

 

 

 

$

45,759,437

 

 

PRINCIPAL
AMOUNT

 

 

 

 

 

 

 

Convertible Notes (Restricted) – 0.2%

 

 

 

 

 

Drug Discovery Technologies – 0.05%

 

 

 

$

198,511

 

Avalon 8% Cvt. Note, due 2006

 

198,511

 

 

 

Healthcare Services – 0.04%

 

 

 

168,337

 

CytoLogix Corporation 6.75% Cvt. Note (b) (e)

 

168,337

 

 

1



 

PRINCIPAL
AMOUNT

 

 

 

VALUE

 

 

 

CONVERTIBLE SECURITIES – continued

 

 

 

 

 

Convertible Notes (Restricted) – continued

 

 

 

 

 

Medical Devices and Diagnostics – 0.08%

 

 

 

$

304,085

 

TherOx, Inc. 6.0% Cvt. Bridge Note, due 2006 (c)

 

$

304,085

 

 

 

 

 

$

670,933

 

 

 

TOTAL CONVERTIBLE SECURITIES
(Cost $62,823,288)

 

$

46,430,370

 

 

SHARES

 

 

 

 

 

 

 

COMMON STOCKS – 77.4%

 

 

 

 

 

Biopharmaceuticals – 21.6%

 

 

 

608,035

 

Cubist Pharmaceuticals, Inc. (a)

 

8,007,821

 

200,001

 

Cubist Pharmaceuticals, Inc. (Restricted) (a)

 

2,634,013

 

155,200

 

Endo Pharmaceuticals Holdings (a)

 

4,078,656

 

97,500

 

Forest Laboratories, Inc. (a)

 

3,787,875

 

20,000

 

Genentech, Inc. (a)

 

1,605,600

 

88,075

 

Genzyme Corporation (a)

 

5,292,427

 

88,200

 

Gilead Sciences, Inc. (a)

 

3,879,918

 

96,700

 

Imclone Systems, Inc. (a)

 

2,994,799

 

69,225

 

Inspire Pharmaceuticals Inc. (a)

 

582,875

 

97,800

 

Martek Biosciences Corporation (a)

 

3,711,510

 

249,400

 

MedImmune, Inc. (a)

 

6,663,968

 

235,000

 

MGI Pharma, Inc. (a)

 

5,113,600

 

615,000

 

Millennium Pharmaceuticals Inc (a)

 

5,701,050

 

315,000

 

Nabi Biopharmaceuticals (a)

 

4,797,450

 

488,740

 

NPS Pharmaceuticals, Inc. (a)

 

5,547,199

 

291,900

 

Pfizer, Inc.

 

8,050,602

 

373,625

 

QLT, Inc. (a)

 

3,893,172

 

167,500

 

The Medicines Company

 

3,917,825

 

464,900

 

Vivus, Inc.

 

1,713,157

 

 

 

 

 

81,973,517

 

 

 

Drug Delivery – 4.3%

 

 

 

443,940

 

Alkermes, Inc. (a)

 

5,868,887

 

218,640

 

Connetics Corporation (a)

 

3,856,810

 

749,933

 

DepoMed, Inc. (a)

 

3,277,207

 

270,520

 

Penwest Pharmaceuticals Co.

 

3,197,546

 

 

 

 

 

16,200,450

 

 

 

Drug Discovery Technologies – 1.0%

 

 

 

236,443

 

Senomyx, Inc. 

 

3,903,674

 

300,000

 

Zyomyx, Inc. (Restricted) (a)

 

3,000

 

 

 

 

 

3,906,674

 

 

 

Emerging Biopharmaceuticals – 21.2%

 

 

 

509,133

 

ACADIA Pharmaceuticals, Inc. 

 

4,276,717

 

387,025

 

Adolor Corporation 

 

3,579,981

 

712,341

 

Ariad Pharmaceuticals, Inc.

 

4,744,191

 

 

2



 

SHARES

 

 

 

VALUE

 

 

 

COMMON STOCKS – continued

 

 

 

 

 

Emerging Biopharmaceuticals – continued

 

 

 

368,125

 

Barrier Therapeutics, Inc.

 

$

2,919,231

 

202,600

 

DOV Pharmaceutical, Inc. (a)

 

3,780,516

 

298,742

 

Dyax Corporation

 

1,410,062

 

912,000

 

Exelixis, Inc.

 

6,776,160

 

596,000

 

Incyte Corporation

 

4,261,400

 

568,600

 

Kosan Biosciences, Inc. 

 

3,002,208

 

470,000

 

Medarex, Inc. (a)

 

3,915,100

 

190,150

 

Momenta Pharmaceuticals, Inc. 

 

3,759,266

 

510,880

 

Myogen, Inc.  (c)

 

3,571,051

 

296,090

 

Neurogen Corporation 

 

2,019,334

 

179,160

 

Nitromed, Inc. 

 

3,484,662

 

522,956

 

Nuvelo, Inc. 

 

4,042,450

 

165,450

 

Progenics Phaarmaceuticals, Inc. 

 

3,451,287

 

312,000

 

Protein Design Labs, Inc. (a)

 

6,305,520

 

616,380

 

Seattle Genetics, Inc. 

 

3,303,797

 

88,004

 

Telik, Inc. (a)

 

1,430,945

 

368,086

 

Tercica, Inc. 

 

3,198,667

 

423,541

 

Theravance, Inc. (a)

 

7,200,197

 

226,760

 

Therion Biologics Corporation (Restricted) (a)

 

2,268

 

 

 

 

 

80,435,010

 

 

 

Generic Pharmaceuticals – 9.6%

 

 

 

112,200

 

Barr Pharmaceuticals Inc (a)

 

5,468,628

 

418,154

 

Impax Laboratories, Inc. (a)

 

6,565,018

 

204,050

 

IVAX Corporation 

 

4,387,075

 

247,000

 

Medicis Pharmaceutical Corporation 

 

7,837,310

 

143,400

 

Par Pharmaceutical Companies, Inc. 

 

4,561,554

 

248,700

 

Teva Pharmaceutical Industries, Ltd. ADR

 

7,744,518

 

 

 

 

 

36,564,103

 

 

 

Healthcare Services – 5.3%

 

 

 

26,125

 

DakoCytomation, Inc. (Restricted)  (f)

 

271,961

 

363,000

 

Eclipsys Corporation

 

5,107,410

 

240,124

 

Emageon, Inc. 

 

3,364,137

 

306,208

 

Syntiro Healthcare Services (Restricted) (a)

 

3,062

 

300,000

 

Tenet Healthcare Corporation (a)

 

3,672,000

 

754,500

 

WebMD Corp (a)

 

7,748,715

 

 

 

 

 

20,167,285

 

 

 

Medical Devices and Diagnostics – 14.4%

 

 

 

122,105

 

Adeza Biomedical Corporation 

 

2,073,343

 

949,200

 

Conor Medsystems, Inc. (Restricted) (a)

 

13,841,709

 

136,000

 

Gen-Probe, Inc. (a)

 

4,927,280

 

131,900

 

IDEXX Laboratories, Inc. (a)

 

8,221,327

 

286,961

 

Intralase Corporation (a)

 

5,630,175

 

160,000

 

Masimo Corporation (Restricted) (a)

 

1,600

 

120,600

 

Medtronic Inc.

 

6,245,874

 

33,735

 

Molecular Devices Corporation (a)

 

729,688

 

 

3



 

SHARES

 

 

 

VALUE

 

 

 

COMMON STOCKS – continued

 

 

 

 

 

Medical Devices and Diagnostics – continued

 

 

 

249,993

 

Orchid Cellmark Inc.

 

$

2,702,425

 

1,020,000

 

Orthovita, Inc. 

 

4,008,600

 

208,529

 

Songbird Hearing, Inc. (Restricted) (a)

 

2,085

 

546,875

 

VNUS Medical Technologies, Inc. (a)

 

6,578,906

 

 

 

 

 

54,963,012

 

 

 

TOTAL COMMON STOCKS
(Cost $254,546,680)

 

$

294,210,051

 

 

PRINCIPAL
AMOUNT

 

 

 

VALUE

 

 

 

SHORT-TERM INVESTMENTS – 10.1%

 

 

 

$

5,000,000

 

American Express Credit Corp.; 3.21% due 07/13/05

 

4,994,650

 

4,000,000

 

American Express Credit Corp.; 3.23% due 07/15/05

 

3,994,976

 

8,900,000

 

ING U.S. Funding LLC.; 3.22% due 07/11/05

 

8,892,040

 

6,700,000

 

Merrill Lynch & Co. Inc.; 3.07% due 07/01/05

 

6,700,000

 

3,400,000

 

United Parcel Service America Inc.; 2.96% due 07/08/05

 

3,398,043

 

2,000,000

 

Verizon Network Funding; 3.11% due 07/06/05

 

1,999,136

 

8,600,000

 

Verizon Network Funding; 3.12% due 07/06/05

 

8,596,273

 

 

 

TOTAL SHORT-TERM INVESTMENTS
(Cost $38,575,118)

 

$

38,575,118

 

 

 

TOTAL INVESTMENTS - 100%
(Cost $355,945,086)

 

$

379,215,539

 

 

 

OTHER ASSETS IN EXCESS OF LIABILITIES - (0%)

 

$

1,056,349

 

 

 

NET ASSETS - (100%)

 

$

380,271,888

 

 


(a)

Non-income producing security.

(b)

Affiliated issuers in which the Fund holds 5% or more of the voting securities (Total Market Value of $28,782,086).

(c)

Including associated warrants.

(d)

Includes 321,000 non-voting shares.

(e)

Variable maturity.

(f)

Foreign Security.

ADR

American Depository Receipt.

 

4



 

H&Q HEALTHCARE INVESTORS

(unaudited)

 

The following table details the acquisition date, cost, carrying value per unit, and value of the Fund’s venture capital and other restricted securities at June 30, 2005, as determined by the Trustees of the Fund.

 

Security (g)

 

Acquisition Date

 

Cost

 

Carrying
Value
per Unit

 

Value

 

 

 

 

 

 

 

 

 

 

 

Agensys, Inc.

 

 

 

 

 

 

 

 

 

Series C Cvt. Pfd.

 

2/14/02

 

$

3,005,073

 

$

3.15

 

$

3,000,000

 

 

 

 

 

 

 

 

 

 

 

Agilix Corporation

 

 

 

 

 

 

 

 

 

Series B Cvt. Pfd.

 

11/8/01

 

3,014,260

 

0.24

 

571,429

 

 

 

 

 

 

 

 

 

 

 

Avalon Pharmaceuticals

 

 

 

 

 

 

 

 

 

Series B Cvt. Pfd.

 

10/22/01

 

3,008,325

 

1.20

 

1,020,523

 

Bridge Loan

 

2/11/05

 

198,511

 

1.00

 

198,511

 

 

 

 

 

 

 

 

 

 

 

CardioNet, Inc.

 

 

 

 

 

 

 

 

 

Series C Cvt. Pfd.

 

5/3/01 - 3/25/03

 

5,549,183

 

3.50

 

5,520,004

 

 

 

 

 

 

 

 

 

 

 

Ceres, Inc.

 

 

 

 

 

 

 

 

 

Series C Cvt. Pfd.

 

12/23/98

 

1,502,620

 

6.00

 

2,250,000

 

Series C-1 Cvt. Pfd.

 

3/31/01

 

111,488

 

6.00

 

164,658

 

Series D Cvt. Pfd.

 

3/14/01

 

1,668,122

 

6.00

 

1,667,802

 

 

 

 

 

 

 

 

 

 

 

Concentric Medical, Inc.

 

 

 

 

 

 

 

 

 

Series B Cvt. Pfd.

 

5/7/02 - 1/24/03

 

3,329,210

 

0.86

 

4,173,528

 

Series C Cvt. Pfd.

 

12/19/03

 

1,500,000

 

0.86

 

1,500,000

 

 

 

 

 

 

 

 

 

 

 

Conor MedSystems, Inc.

 

 

 

 

 

 

 

 

 

Restricted Common

 

10/23/2003-8/6/04

 

3,056,876

 

14.58

 

13,841,709

 

 

 

 

 

 

 

 

 

 

 

Corus Pharma, Inc.

 

 

 

 

 

 

 

 

 

Series C Cvt. Pfd.

 

4/8/04

 

3,002,344

 

1.16

 

3,000,000

 

 

 

 

 

 

 

 

 

 

 

Cubist Pharmaceuticals, Inc.

 

 

 

 

 

 

 

 

 

Restricted Common

 

8/14/03

 

450,237

 

13.17

 

2,634,013

 

 

 

 

 

 

 

 

 

 

 

CytoLogix Corporation

 

 

 

 

 

 

 

 

 

Series A Cvt. Pfd.

 

1/13/98-7/21/99

 

1,622,895

 

0.83

 

399,984

 

Series B Cvt. Pfd.

 

1/11/01

 

760,284

 

0.83

 

187,382

 

Cvt. Note

 

5/29/02

 

168,337

 

1.00

 

168,337

 

 

 

 

 

 

 

 

 

 

 

DakoCytomation, Inc.

 

 

 

 

 

 

 

 

 

Restricted Common

 

6/14/04

 

1,102,920

 

10.41

 

271,961

 

 

 

 

 

 

 

 

 

 

 

EPR, Inc.

 

 

 

 

 

 

 

 

 

Series A Cvt. Pfd.

 

3/9/94

 

1,000,409

 

0.01

 

2,222

 

 

 

 

 

 

 

 

 

 

 

Galileo Pharmaceuticals, Inc.

 

 

 

 

 

 

 

 

 

Series F-1 Cvt. Pfd.

 

8/18/00

 

3,002,895

 

0.35

 

489,556

 

 

 

 

 

 

 

 

 

 

 

I-trax, Inc.

 

 

 

 

 

 

 

 

 

Series A Cvt. Pfd.

 

3/18/04

 

4,003,650

 

16.40

 

2,624,000

 

 

 

 

 

 

 

 

 

 

 

Masimo Corporation

 

 

 

 

 

 

 

 

 

Series D Cvt. Pfd.

 

8/14/96

 

1,120,041

 

11.00

 

1,760,000

 

Restricted Common

 

3/31/98

 

0

 

0.01

 

1,600

 

 

 

 

 

 

 

 

 

 

 

OmniSonics Medical Technologies, Inc.

 

 

 

 

 

 

 

 

 

Series B Cvt. Pfd.

 

5/24/01

 

2,409,023

 

1.34

 

2,181,224

 

Series C Cvt. Pfd.

 

10/1/03

 

1,800,336

 

1.16

 

1,800,000

 

 

 

 

 

 

 

 

 

 

 

PHT Corporation

 

 

 

 

 

 

 

 

 

Series D Cvt. Pfd.

 

7/23/01

 

4,205,754

 

0.78

 

4,200,000

 

Series E Cvt. Pfd.

 

9/12/03 - 10/14/04

 

941,669

 

0.78

 

939,506

 

 



 

Raven biotechnologies, Inc.

 

 

 

 

 

 

 

 

 

Series B Cvt. Pfd.

 

12/12/00

 

$

3,001,725

 

$

0.83

 

$

1,509,091

 

Series C Cvt. Pfd.

 

11/26/02

 

2,331,600

 

0.83

 

2,331,600

 

Series D Cvt. Pfd.

 

6/23/05

 

1,200,000

 

0.33

 

1,200,000

 

 

 

 

 

 

 

 

 

 

 

Songbird Hearing, Inc.

 

 

 

 

 

 

 

 

 

Restricted Common

 

12/14/00

 

3,004,861

 

0.01

 

2,085

 

 

 

 

 

 

 

 

 

 

 

Syntiro Heathcare Services

 

 

 

 

 

 

 

 

 

Restricted Common

 

2/5/97

 

1,200,325

 

0.01

 

3,062

 

 

 

 

 

 

 

 

 

 

 

Therion Biologics Corporation

 

 

 

 

 

 

 

 

 

Series A Cvt. Pfd.

 

8/20/96-10/16/96

 

444,850

 

1.22

 

57,837

 

Series B Cvt. Pfd.

 

6/22/99

 

901,393

 

1.22

 

292,800

 

Series C Cvt. Pfd.

 

9/26/01-10/15/01

 

1,529,348

 

1.22

 

497,409

 

Series C-2 Units

 

8/13/03

 

59,998

 

1.22

 

40,665

 

Sinking Fund Cvt. Pfd.

 

10/18/94-8/20/96

 

721,291

 

0.01

 

361

 

Restricted Common

 

7/12/90-1/25/96

 

511,365

 

0.01

 

2,268

 

 

 

 

 

 

 

 

 

 

 

TherOx, Inc.

 

 

 

 

 

 

 

 

 

Series H Cvt. Pfd.

 

9/11/00

 

3,002,506

 

0.38

 

247,826

 

Cvt. Bridge Note

 

1/28/04

 

304,085

 

1.00

 

304,085

 

 

 

 

 

 

 

 

 

 

 

Xanthus Life Sciences, Inc.

 

 

 

 

 

 

 

 

 

Series B Cvt. Pfd.

 

12/5/03

 

2,101,320

 

1.00

 

2,100,000

 

 

 

 

 

 

 

 

 

 

 

Zyomyx, Inc.

 

 

 

 

 

 

 

 

 

New Common

 

2/19/99 - 7/22/04

 

3,602,065

 

0.01

 

3,000

 

Series A New Cvt. Pfd.

 

1/12/04

 

299,700

 

0.10

 

30,000

 

Series B New Cvt. Pfd.

 

2/19/99-1/12/04

 

468

 

0.10

 

30

 

 

 

 

 

$

75,751,362

 

 

 

$

63,190,068

(h)

 


(g) See Schedule of Investments and corresponding footnotes for more information on each issuer.

(h) Represents 17% of the Fund’s net assets as of June 30, 2005.

 



 

Item 2.  Controls and Procedures.

 

(a.)          The registrant’s principal executive officer and principal financial officer have concluded, based on their evaluation of the registrant’s disclosure controls and procedures as conducted within 90 days of the filing date of this report, that these disclosure controls and procedures are adequately designed and are operating effectively to ensure that information required to be disclosed by the registrant on Form N-Q is (i) accumulated and communicated to the investment company’s management, including its certifying officers, to allow timely decisions regarding required disclosure; and (ii) recorded, processed, summarized and reported within the time periods specified in the Securities and Exchange Commission’s rules and forms.

 

(b.)              There were no changes in the registrant’s internal control over financial reporting (as defined in Rule 30a-3(d) under the 1940 Act that occurred during the registrant’s last fiscal quarter that has materially affected, or is reasonably likely to materially affect, the registrant’s internal control over financial reporting.

 

Item 3. Exhibits.

 

Separate certifications for each principal executive officer and principal financial officer of the registrant as required by Rule 30a-2(a) under the Act (17 CFR 270.30a-2(a)).  Filed herewith.

 



 

SIGNATURES

 

Pursuant to the requirements of the Securities and Exchange Act of 1934 and the Investment Company Act of 1940, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

 

(Registrant)

  H&Q Healthcare Investors

 

 

By (Signature and Title)

 

 

 

/s/ Daniel Omstead, President

 

Date

  August 26, 2005

 

 

Pursuant to the requirements of the Securities and Exchange Act of 1934 and the Investment Company Act of 1940, this report has been signed below by the following persons on behalf of the registrant and in the capacities and on the dates indicated.

 

By (Signature and Title)*

 

 

 

/s/ Kathleen Eckert, Treasurer

 

Date

  August 26, 2005