UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549


                                  SCHEDULE 13G

                  Under the Securities and Exchange Act of 1934

                             (Amendment No. 2)*


                                 Alfacell Corp.
--------------------------------------------------------------------------------
                                (Name of Issuer)


                     Common Stock, $.001 par value per share
--------------------------------------------------------------------------------
                         (Title of Class of Securities)


                                    015404106
--------------------------------------------------------------------------------
                                 (CUSIP Number)


                                December 31, 2006
--------------------------------------------------------------------------------
            (Date of Event Which Requires Filing of this Statement)


     Check the appropriate box to designate the rule pursuant to which this
Schedule is filed:

          [_] Rule 13d-1(b)

          [X] Rule 13d-1(c)

          [_] Rule 13d-1(d)

----------
*    The remainder of this cover page shall be filled out for a reporting
     person's initial filing on this form with respect to the subject class of
     securities, and for any subsequent amendment containing information which
     would alter the disclosures provided in a prior cover page.

     The information required in the remainder of this cover page shall not be
deemed to be "filed" for the purpose of Section 18 of the Securities Exchange
Act of 1934 or otherwise subject to the liabilities of that section of the Act
but shall be subject to all other provisions of the Act (however, see the
Notes).





CUSIP No. 015404106                   13G                    Page 2 of 11 Pages

________________________________________________________________________________
1. NAME OF REPORTING PERSONS
     I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

         Europa International, Inc.
________________________________________________________________________________
2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                 (a) [_]
                                                                 (b) [X]
                                                                 Joint Filer
________________________________________________________________________________
3. SEC USE ONLY

________________________________________________________________________________
4. CITIZENSHIP OR PLACE OF ORGANIZATION

         British Virgin Islands
________________________________________________________________________________
  NUMBER OF    5.   SOLE VOTING POWER

   SHARES           0
               _________________________________________________________________
BENEFICIALLY   6.   SHARED VOTING POWER

  OWNED BY          2,308,178
               _________________________________________________________________
    EACH       7.   SOLE DISPOSITIVE POWER

  REPORTING         0
               _________________________________________________________________
   PERSON      8.   SHARED DISPOSITIVE POWER

    WITH            2,308,178
________________________________________________________________________________
9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

                  2,308,178
________________________________________________________________________________
10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*

                                                                          [_]
________________________________________________________________________________
11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

                  5.05%
________________________________________________________________________________
12. TYPE OF REPORTING PERSON*

                  CO
________________________________________________________________________________
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!





CUSIP No. 015404106                   13G                    Page 3 of 11 Pages

________________________________________________________________________________
1. NAME OF REPORTING PERSONS
     I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)


         Knoll Capital Management, LP
________________________________________________________________________________
2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                 (a) [_]
                                                                 (b) [X]
                                                                   Joint Filer
________________________________________________________________________________
3. SEC USE ONLY

________________________________________________________________________________
4. CITIZENSHIP OR PLACE OF ORGANIZATION

         Delaware
________________________________________________________________________________
  NUMBER OF    5.   SOLE VOTING POWER

   SHARES           0
               _________________________________________________________________
BENEFICIALLY   6.   SHARED VOTING POWER

  OWNED BY          4,567,887
               _________________________________________________________________
    EACH       7.   SOLE DISPOSITIVE POWER

  REPORTING         0
               _________________________________________________________________
   PERSON      8.   SHARED DISPOSITIVE POWER

    WITH            4,567,887
________________________________________________________________________________
9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

                  4,567,887
________________________________________________________________________________
10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*

                                                                          [_]
________________________________________________________________________________
11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

                  9.85%
________________________________________________________________________________
12. TYPE OF REPORTING PERSON*

                  PN
________________________________________________________________________________
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!






CUSIP No. 015404106                   13G                    Page 4 of 11 Pages

________________________________________________________________________________
1. NAME OF REPORTING PERSONS
     I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

         Fred Knoll
________________________________________________________________________________
2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                 (a) [_]
                                                                 (b) [X]
                                                                  Joint Filer
________________________________________________________________________________
3. SEC USE ONLY


________________________________________________________________________________
4. CITIZENSHIP OR PLACE OF ORGANIZATION

         USA
________________________________________________________________________________
  NUMBER OF    5.   SOLE VOTING POWER

   SHARES           0
               _________________________________________________________________
BENEFICIALLY   6.   SHARED VOTING POWER

  OWNED BY          4,567,887
               _________________________________________________________________
    EACH       7.   SOLE DISPOSITIVE POWER

  REPORTING         0
               _________________________________________________________________
   PERSON      8.   SHARED DISPOSITIVE POWER

    WITH            4,567,887
________________________________________________________________________________
9.  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

                  4,567,887
________________________________________________________________________________
10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES* [_]

________________________________________________________________________________
11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

                  9.85%
________________________________________________________________________________
12. TYPE OF REPORTING PERSON*

                  IN
________________________________________________________________________________
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!





CUSIP No. 015404106                   13G                    Page 5 of 11 Pages


Item 1(a).  Name of Issuer:

                           Alfacell Corporation (the "Issuer")

            ____________________________________________________________________

Item 1(b).  Address of Issuer's Principal Executive Offices:

                          225 Belleville Avenue
                          Bloomfield, New Jersey 07003

            ____________________________________________________________________

Item 2(a).  Name of Persons Filing:

                          Europa International, Inc. ("Europa")
                          Knoll Capital Management LP ("KCMLP")
                          Fred Knoll ("Knoll")

            ____________________________________________________________________

Item 2(b).  Address of Principal Business Office, or if None, Residence:

                          The principal business address for each of Europa,
                          KCMLP and Knoll is 666 Fifth Avenue, Suite 3702, New
                          York, New York 10103.

            ____________________________________________________________________

Item 2(c).  Citizenship:


                          Europa is a company organized under the laws of the
                          British Virgin Islands.
                          KCMLP is a Limited Partnership formed and existing
                          under the laws of the State of Delaware.
                          Knoll is a citizen of the United States.

            ____________________________________________________________________

Item 2(d).  Title of Class of Securities:


                          This statement on Schedule 13G is being filed with
                          respect to Common Stock, $0.001 par value per share
                          (the "Common Stock") of the Issuer.

            ____________________________________________________________________

Item 2(e).  CUSIP Number:


                           015404106
            ____________________________________________________________________




CUSIP No. 015404106                   13G                    Page 6 of 11 Pages


Item 3.     If This Statement  is Filed  Pursuant to  Rule 13d-1(b), or 13d-2(b)
            or (c), Check Whether the Person Filing is a: Not Applicable.

     (a)       [_] Broker or dealer registered under Section 15 of the Exchange
                   Act.

     (b)       [_] Bank as defined in Section 3(a)(6) of the Exchange Act.

     (c)       [_] Insurance company as defined in Section 3(a)(19) of the
                   Exchange Act.

     (d)       [_] Investment company registered under Section 8 of the
                   Investment Company Act.

     (e)       [_] An investment adviser in accordance with Rule
                   13d-1(b)(1)(ii)(E);

     (f)       [_] An employee benefit plan or endowment fund in accordance with
                   Rule 13d-1(b)(1)(ii)(F);

     (g)       [_] A parent holding company or control person in accordance with
                   Rule 13d-1(b)(1)(ii)(G);

     (h)       [_] A savings association as defined in Section 3(b) of the
                   Federal Deposit Insurance Act;

     (i)       [_] A church plan that is excluded from the definition of an
                   investment company under Section 3(c)(14) of the Investment
                   Company Act;

     (j)       [_] Group, in accordance with Rule 13d-1(b)(1)(ii)(J).




CUSIP No. 015404106                   13G                    Page 7 of 11 Pages


Item 4.  Ownership.

     Provide the following information regarding the aggregate number and
percentage of the class of securities of the issuer identified in Item 1.

     (a) Amount beneficially owned:

                  As of the date of this filing:

                  Europa owns 2,308,178 shares of the Issuer's Common Stock
consisting of (i) 1,608,535 shares of the Issuer's Common Stock; and (ii)
immediately exercisable Warrants to purchase 699,643 shares of the Common Stock
of the Issuer.

                  Each of KCMLP and Knoll beneficially own 4,567,887 shares of
the Issuer's Common Stock consisting of (i) 1,608,535 shares of the Issuer's
Common Stock owned by Europa; (ii) immediately exercisable Warrants to purchase
699,643 shares of the Common Stock of the Issuer owned by Europa; (iii)
1,540,716 shares of the Issuer's Common Stock owned by Knoll Capital Fund II
Master Fund, Ltd. (the "Knoll Fund"); (iv) immediately exercisable Warrants to
purchase 699,643 shares of the Common Stock of the Issuer owned by the Knoll
Fund; and (v) 19,350 shares of the Issuer's Common Stock owned by Knoll Special
Opportunities Fund ("Opportunities"). KCMLP is the investment manager of Europa
and a manager of KOM Capital Management, LLC ("KOM"), the investment manager of
each of the Knoll Fund and Opportunities. Knoll is the President of KCMLP.

          ______________________________________________________________________

     (b) Percent of class: As of the date of this filing (taking into
consideration that 45,008,401 shares of the Issuer's Common Stock is issued and
outstanding as reported in the Issuer's Form 10-Q for the period ended October
31, 2006 and taking into consideration the immediately exercisable Warrants
owned by each of Europa and the Knoll Fund).

                  The 2,308,178 shares of the Issuer's Common Stock owned by
Europa constituted 5.05% of the shares outstanding.

                  The 4,567,887 shares of the Issuer's Common Stock beneficially
owned by each of KCMLP and Knoll constituted 9.85% of the shares outstanding.
          ______________________________________________________________________

     (c) Number of shares as to which such person has:

                  (i) Sole power to vote or direct the vote:

                  Not Applicable.

                  (ii) Shared power to vote or to direct the vote:

                  KCMLP and Knoll share the power to vote or direct the vote of
those shares of Common Stock owned by Europa, the Knoll Fund and Opportunities.




                  Europa shares the power to vote or direct the vote of those
shares of Common Stock owned by it with KCMLP and Knoll.

                  (iii) Sole power to dispose or direct the disposition of:

                  Not Applicable.

                  (iv) Shared power to dispose or direct the disposition of:

                  KCMLP and Knoll share the power to dispose of or direct the
disposition of those shares of Common Stock owned by Europa, the Knoll Fund and
Opportunities.

                  Europa shares the power to dispose of or direct the
disposition of those shares of Common Stock owned by it with KCMLP and Knoll.

                  The 4,567,887 shares of the Common Stock of the Issuer covered
by this Schedule 13G are beneficially owned by KCMLP as the investment manager
for (i) Europa, an equity fund which holds 2,308,178 shares of the Common Stock
on the date hereof; (ii) the Knoll Fund, an equity fund which holds 2,240,359
shares of the Common Stock on the date hereof; and (iii) Opportunities which
holds 19,350 shares of the Common Stock on the date hereof. Knoll is the
President of KCMLP and as such has the power to vote and dispose of the shares
of Common Stock owned by each of Europa, the Knoll Fund and Opportunities.


Item 5.  Ownership of Five Percent or Less of a Class.

     If this statement is being filed to report the fact that as of the date
hereof the reporting person has ceased to be the beneficial owner of more than
five percent of the class of securities check the following [ ].


         _______________________________________________________________________

Item 6.  Ownership of More Than Five Percent on Behalf of Another Person.

         As set forth in Item 4(c), the shares of Common Stock covered by this
Schedule 13G are owned by persons other than Europa, KCMLP and Knoll, none of
whom holds five percent or more of the securities reported herein.
_______________________________________________________________________

Item     7. Identification and Classification of the Subsidiary Which Acquired
         the Security Being Reported on by the Parent Holding Company or Control
         Person.


                           Not Applicable
         _______________________________________________________________________

Item 8.  Identification  and  Classification  of Members of the Group.


                           Not Applicable
         _______________________________________________________________________




Item 9.  Notice of Dissolution of Group.


                           Not Applicable.
          ______________________________________________________________________

Item 10.  Certifications.

     (a)  The following certification shall be included if the statement is
          filed pursuant to Rule 13d-1(c):

          By signing below I certify that, to the best of my knowledge and
belief, the securities referred to above were not acquired and are not held for
the purpose of or with the effect of changing or influencing the control of the
issuer of the securities and were not acquired and are not held in connection
with or as a participant in any transaction having that purpose or effect.






                                    SIGNATURE

     After reasonable inquiry and to the best of my knowledge and belief, I
certify that the information set forth in this statement is true, complete and
correct.

Dated: February 14, 2007                    KNOLL CAPITAL MANAGEMENT, LP


                                            By:    /s/ Fred Knoll
                                                   -----------------------------
                                            Name:  Fred Knoll
                                                   -----------------------------
                                            Title: President
                                                   -----------------------------


Dated:  February 14, 2007                          /s/Fred Knoll
                                                   -----------------------------
                                                   Fred Knoll


Dated:  February 14, 2007                   EUROPA INTERNATIONAL, INC.


                                            By:    /s/ Fred Knoll
                                                   -----------------------------
                                            Name:  Fred Knoll
                                                   ----------------------------
                                            Title: Investment Manager
                                                   -----------------------------


Note. Schedules filed in paper format shall include a signed original and five
copies of the schedule, including all exhibits. See Rule 13d-7 for other parties
for whom copies are to be sent.

Attention. Intentional misstatements or omissions of fact constitute federal
criminal violations (see 18 U.S.C. 1001).





                             JOINT FILING AGREEMENT


         The undersigned acknowledge and agree that the foregoing statement on
Schedule 13G is filed on behalf of each of the undersigned and that all
subsequent amendments to this statement on Schedule 13G shall be filed on behalf
of each of the undersigned without the necessity of filing additional joint
filing agreements. The undersigned acknowledge that each shall be responsible
for the timely fling of such amendments, and for the completeness and accuracy
of the information concerning it contained therein, but shall not be responsible
for the completeness and accuracy of the information concerning the others,
except to the extent that it knows or has reason to believe that such
information is inaccurate.


 Dated: February 14, 2007                   KNOLL CAPITAL MANAGEMENT, LP


                                            By:    /s/ Fred Knoll
                                                   -----------------------------
                                            Name:  Fred Knoll
                                                   -----------------------------
                                            Title: President
                                                   -----------------------------


Dated:  February 14, 2007                       /s/ Fred Knoll
                                                --------------------------------
                                                Fred Knoll

Dated:  February 14, 2007                   EUROPA INTERNATIONAL, INC.


                                            By:    /s/ Fred Knoll
                                                   -----------------------------
                                            Name:  Fred Knoll
                                                   -----------------------------
                                            Title: Investment Manager