UNITED STATES
                        SECURITIES EXCHANGE COMMISSION
                            Washington, D.C. 20549

------------------------------------------------------------------------------

                                 SCHEDULE 13G

                   Under the Securities Exchange Act of 1934
                                (Amendment No. )

                            FIBROCELL SCIENCE, INC.
                            -----------------------
                               (Name of Issuer)


                   Common Stock, $0.001 par value per share
                   ---------------------------------------
                        (Title of Class of Securities)


                                   315721100
                                   ---------
                                (CUSIP Number)


                               November 11, 2009
                               -----------------
            (Date of Event which Requires Filing of this Statement)


Check  the appropriate box to designate the rule pursuant to which this Schedule
is filed:

                               [ ] Rule 13d-1(b)

                               [X] Rule 13d-1(c)

                               [ ] Rule 13d-1(d)

* The remainder of this cover page shall be filled out for a reporting  person's
initial filing on this form with respect to the subject class of securities, and
for any  subsequent  amendment  containing  information  which  would  alter the
disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the  Securities  Exchange  Act of
1934 ("Act") or otherwise  subject to the liabilities of that section of the Act
but  shall be  subject  to all other  provisions  of the Act  (however,  see the
Notes).


                         Continued on following pages
                              Page 1 of 10 Pages
                             Exhibit Index: Page 9



                                                            Page 2 of 10 Pages

-------------------------------------------------------------------------------
1.        Names of Reporting Persons.

          I.R.S. Identification Nos. of above persons (entities only).

          AKANTHOS CAPITAL MANAGEMENT, LLC
-------------------------------------------------------------------------------
2.        Check the Appropriate Box if a Member of a Group

          (a) [  ]

          (b) [  ]
-------------------------------------------------------------------------------
3.        SEC Use Only
-------------------------------------------------------------------------------
4.        Citizenship or Place of Organization

          Delaware
-------------------------------------------------------------------------------
                      5.       Sole Voting Power                  1,581,565
Number of Shares      ---------------------------------------------------------
Beneficially Owned    6.       Shared Voting Power                None
by Each Reporting     ---------------------------------------------------------
Person With           7.       Sole Dispositive Power             1,581,565
                      ---------------------------------------------------------
                      8.       Shared Dispositive Power           None
-------------------------------------------------------------------------------
9.        Aggregate Amount Beneficially Owned by Each Reporting Person

          1,581,565
-------------------------------------------------------------------------------
10.       Check if the Aggregate Amount in Row (9) Excludes Certain Shares
          (See Instructions)

          [  ]
-------------------------------------------------------------------------------
11.       Percent of Class Represented by Amount in Row (9)

          10.78% based on 14,666,666 Shares outstanding as of
          November 20, 2009.
-------------------------------------------------------------------------------
12.       Type of Reporting Person:

          OO




                                                            Page 3 of 10 Pages

-------------------------------------------------------------------------------
Names of Reporting Persons.

I.R.S. Identification Nos. of above persons (entities only).

AKANTHOS ARBITRAGE MASTER FUND, L.P.
-------------------------------------------------------------------------------
Check the Appropriate Box if a Member of a Group

(a) [  ]

(b) [  ]
-------------------------------------------------------------------------------
SEC Use Only
-------------------------------------------------------------------------------
Citizenship or Place of Organization

Cayman Islands
-------------------------------------------------------------------------------
                      13.      Sole Voting Power                  1,320,700
Number of Shares      ---------------------------------------------------------
Beneficially Owned    14.      Shared Voting Power                None
by Each Reporting     ---------------------------------------------------------
Person With           15.      Sole Dispositive Power             1,320,700
                      ---------------------------------------------------------
                      16.      Shared Dispositive Power           None
-------------------------------------------------------------------------------
Aggregate Amount Beneficially Owned by Each Reporting Person

1,320,700
-------------------------------------------------------------------------------
Check if the Aggregate Amount in Row (9) Excludes Certain Shares
(See Instructions)

[  ]
-------------------------------------------------------------------------------
Percent of Class Represented by Amount in Row (9)

9.00% based on 14,666,666 Shares outstanding as of November 20, 2009.
-------------------------------------------------------------------------------
Type of Reporting Person:

PN




                                                            Page 4 of 10 Pages

-------------------------------------------------------------------------------
1.        Names of Reporting Persons.

          I.R.S. Identification Nos. of above persons (entities only).

          MICHAEL KAO
-------------------------------------------------------------------------------
2.        Check the Appropriate Box if a Member of a Group

          (a) [  ]

          (b) [  ]
-------------------------------------------------------------------------------
3.        SEC Use Only
-------------------------------------------------------------------------------
4.        Citizenship or Place of Organization

          United States of America
-------------------------------------------------------------------------------
                      5.       Sole Voting Power                  1,581,565
Number of Shares      ---------------------------------------------------------
Beneficially Owned    6.       Shared Voting Power                None
by Each Reporting     ---------------------------------------------------------
Person With           7.       Sole Dispositive Power             1,581,565
                      ---------------------------------------------------------
                      8.       Shared Dispositive Power           None
-------------------------------------------------------------------------------
9.        Aggregate Amount Beneficially Owned by Each Reporting Person

          1,581,565
-------------------------------------------------------------------------------
10.       Check if the Aggregate Amount in Row (9) Excludes Certain Shares
          (See Instructions)

          [  ]
-------------------------------------------------------------------------------
11.       Percent of Class Represented by Amount in Row (9)

          10.78% based on 14,666,666 Shares outstanding as of November 20, 2009.
-------------------------------------------------------------------------------
12.       Type of Reporting Person:

          IN





                                                             Page 5 of 10 Pages


Item 1(a).        Name of Issuer:

                  Fibrocell Science, Inc. (the "Issuer")

Item 1(b).        Address of Issuer's Principal Executive Offices:

                  405 Eagleview Boulevard, Exton, Pennsylvania 19341

Item 2(a).        Name of Person Filing

                  This  Statement  is filed on behalf  of each of the  following
persons (collectively, the "Reporting Persons"):

                  i)   Akanthos Capital Management, LLC ("Akanthos Capital
                       Management");

                  ii)  Akanthos Arbitrage Master Fund, L.P., ("Akanthos Master
                       Fund"); and

                  iii) Michael Kao ("Mr. Kao").

                  This Statement  relates to Shares (as defined herein) held for
the  account of Akanthos  Master  Fund  and  for the account of certain  managed
account ("Managed  Account").  Akanthos Capital  Management serves as investment
manager and general  partner to  Akanthos  Master Fund and serves as  investment
advisor to the Managed Account.  In such capacity,  Akanthos Capital  Management
may be deemed to have  voting and  dispositive  power  over the Shares  held for
Akanthos Master Fund and the Managed Account. Mr. Kao is the Manager of Akanthos
Capital Management.  In such capacity,  Mr. Kao may be deemed to have voting and
dispositive  power over the Shares held for Akanthos Master Fund and the Managed
Account.

Item 2(b).        Address of Principal Business Office or, if None, Residence:

                  The  address  of the  principal  business  office  of  each of
Akanthos  Capital  Management  and Mr.  Kao is 21700  Oxnard  St.,  Suite  1520,
Woodland Hills CA 91367-7584.

                  The  address of the  principal  business  office for  Akanthos
Master Fund is c/o Appleby Corporate  Services (Cayman) Ltd.,  Clifton House, 75
Fort Street, P.O. Box 1350 GT, Grand Cayman, Cayman Islands.

Item 2(c).        Citizenship:

                  i)   Akanthos Capital Management is a Delaware limited
                       liability company;

                  ii)  Akanthos Master Fund is a Cayman Islands limited
                       partnership; and

                  iii) Mr. Kao is a citizen of the United States of America.

Item 2(d).        Title of Class of Securities:

                  Common Stock (the "Shares")

Item 2(e).        CUSIP Number:

                  315721100



                                                              Page 6 of 10 Pages

Item 3.           If This Statement is Filed Pursuant to  ss.ss.240.13d-1(b)  or
                  240.13d-2(b) or (c), Check Whether the Person Filing is a:

                  This Item 3 is not applicable.

Item 4.           Ownership:

Item 4(a)         Amount Beneficially Owned:

                  As of November 11, 2009, each of Akanthos  Capital  Management
and Mr. Kao may be deemed to be the beneficial owner of 1,581,565  Shares.  This
amount consists of: (A) 1,320,700 Shares held for the account of Akanthos Master
Fund; and (B) 260,865 Shares held for the account of the Managed Account.

Item 4(b)         Percent of Class:

                  The  number  of  Shares  of  which  each of  Akanthos  Capital
Management  and Mr.  Kao may be deemed to be the  beneficial  owner  constitutes
approximately  10.78% of the total number of Shares  outstanding.  The number of
Shares of which Akanthos  Master Fund may be deemed to be the  beneficial  owner
constitutes  approximately  9.00% of the total  number  of  Shares  outstanding.
(Based upon information provided in the Issuer's Form 10-Q filed on November 24,
2009, there were approximately  14,666,666 Shares outstanding as of November 20,
2009).

Item 4(c)         Number of Shares of which such person has:

Akanthos Capital Management and Mr. Kao:
----------------------------------------

(i) Sole power to vote or direct the vote:                            1,581,565

(ii) Shared power to vote or direct the vote:                                 0

(iii) Sole power to dispose or direct the disposition of:             1,581,565

(iv) Shared power to dispose or direct the disposition of:                    0


Akanthos Master Fund:
---------------------

(i) Sole power to vote or direct the vote:                            1,320,700

(ii) Shared power to vote or direct the vote:                                 0

(iii) Sole power to dispose or direct the disposition of:             1,320,700

(iv) Shared power to dispose or direct the disposition of:                    0


Item 5.           Ownership of Five Percent or Less of a Class:

                  This Item 5 is not applicable.



                                                              Page 7 of 10 Pages


Item 6.           Ownership of More than Five Percent on Behalf of Another
                  Person:

                  This Item 6 is not applicable.

Item 7.           Identification  and  Classification  of the  Subsidiary  Which
                  Acquired  the Security Being Reported on By the Parent Holding
                  Company:

                  See disclosure in Item 2 hereof.

Item 8.           Identification and Classification of Members of the Group:

                  This Item 8 is not applicable.

Item 9.           Notice of Dissolution of Group:

                  This Item 9 is not applicable.

Item 10.          Certification:

                  By signing below each of the Reporting Persons certifies that,
to the best of their knowledge and belief, the securities referred to above were
not  acquired and are not held for the purpose of or with the effect of changing
or influencing the control of the Issuer of the securities and were not acquired
and are not  held in  connection  with or as a  participant  in any  transaction
having that purpose or effect.



                                                              Page 8 of 10 Pages

                                    SIGNATURE

          After reasonable inquiry and to the best of my knowledge and belief, I
certify that the information  set forth in this statement is true,  complete and
correct.

Date: December 3, 2009                   AKANTHOS CAPITAL MANAGEMENT, LLC


                                         By: /s/ Michael Kao
                                             ---------------
                                         Name:   Michael Kao
                                         Title:  Manager

Date: December 3, 2009                   AKANTHOS ARBITRAGE MASTER FUND, L.P.
                                         By: Akanthos Capital Management, LLC
                                             its general partner


                                         By: /s/ Michael Kao
                                             ---------------
                                         Name:   Michael Kao
                                         Title:  Manager

Date: December 3, 2009                   Michael Kao


                                         /s/ Michael Kao
                                         ---------------



                                                              Page 9 of 10 Pages

                                  EXHIBIT INDEX


Ex.                                                                     Page No.
---                                                                     --------
           A Joint Filing  Agreement,  dated December 3, 2009
           by and among  Akanthos  Capital  Management,  LLC,
           Akanthos Arbitrage Master Fund, L.P. and Michael Kao               10



                                                             Page 10 of 10 Pages

                                    EXHIBIT A

                             JOINT FILING AGREEMENT

          The  undersigned  hereby agree that the statement on Schedule 13G with
respect to the Common Stock of Fibrocell  Science,  Inc. dated as of December 3,
2009 is, and any  amendments  thereto  (including  amendments  on Schedule  13D)
signed  by each of the  undersigned  shall  be,  filed on  behalf  of each of us
pursuant to and in accordance  with the  provisions  of Rule 13d-1(k)  under the
Securities Exchange Act of 1934, as amended.

Date: December 3, 2009                   AKANTHOS CAPITAL MANAGEMENT, LLC


                                         By: /s/ Michael Kao
                                             ---------------
                                         Name:   Michael Kao
                                         Title:  Manager

Date: December 3, 2009                   AKANTHOS ARBITRAGE MASTER FUND, L.P.
                                         By: Akanthos Capital Management, LLC
                                             its general partner


                                         By: /s/ Michael Kao
                                             ---------------
                                         Name:   Michael Kao
                                         Title:  Manager

Date: December 3, 2009                   Michael Kao


                                         /s/ Michael Kao
                                         ---------------