SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                  SCHEDULE 13D

                   Under the Securities Exchange Act of 1934
                               (Amendment No.2)*

                                Biogen Idec Inc.
                                (Name of Issuer)

                        Common Stock, Par Value $0.0005
                         (Title of Class of Securities)

                                   09062X103
                                 (CUSIP Number)

                               Marc Weitzen, Esq.
                                Icahn Capital LP
                          767 Fifth Avenue, 47th Floor
                            New York, New York 10153
                                 (212) 702-4388
                 (Name, Address and Telephone Number of Person
               Authorized to Receive Notices and Communications)

                                January 27, 2010
            (Date of Event which Requires Filing of this Statement)

If  the filing person has previously filed a statement on Schedule 13G to report
the  acquisition  that  is  the subject of this Schedule 13D, and is filing this
schedule  because  of  Section 240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check
the  following  box  /  /.

NOTE:  Schedules  filed in paper format shall include a signed original and five
copies of the schedule, including all exhibits. See Rule 13d-7 for other parties
to  whom  copies  are  to  be  sent.

*The  remainder  of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities, and
for  any  subsequent  amendment  containing  information  which  would  alter
disclosures  provided  in  a  prior  cover  page.

The information required on the remainder of this cover page shall not be deemed
to  be  "filed"  for the purpose of Section 18 of the Securities Exchange Act of
1934  ("Act") or otherwise subject to the liabilities of that section of the Act
but  shall  be  subject  to  all  other  provisions of the Act (however, see the
Notes).



                                  SCHEDULE 13D

Item 1. Security and Issuer

     The  Schedule  13D,  as  amended,  filed  with  the Securities and Exchange
Commission  on August 11, 2008 by the Reporting Persons (the "Initial 13D") with
respect  to the shares of Common Stock, par value $0.0005 (the "Shares"), issued
by  Biogen  Idec Inc. (the "Issuer") is hereby amended to furnish the additional
information  set  forth  herein.  All capitalized terms contained herein but not
otherwise defined shall have the meanings ascribed to such terms in the Schedule
13D.

Item 4. Purpose of Transaction

Item 4 of the Schedule 13D is hereby amended by the addition of the following:

     On  January  27,  2010,  entities  affiliated  with Mr. Icahn delivered the
"Stockholders'  Notice  of  Nomination  of Persons for Election as Directors and
Other  Proposed  Business  at  the 2010 Annual Meeting of Stockholders of Biogen
Idec Inc." (the "Notice"), a copy of which is attached hereto as Exhibit I. Such
Notice  states  the intention of High River, Icahn Partners, Icahn Master, Icahn
Master II and Icahn Master III: (i) to seek to nominate Dr. Thomas F. Deuel, Dr.
Eric  Rowinsky  and  Professor  Richard  A.  Young  for election to the Board of
Directors  of the Issuer at the 2010 annual meeting of stockholders; and (ii) to
propose  certain  amendments  to the Issuer's Second Amended and Restated Bylaws
that  would  limit  the  size  of  the  Board  of  Directors  to  twelve.

SECURITY  HOLDERS  ARE  ADVISED  TO READ THE PROXY STATEMENT AND OTHER DOCUMENTS
RELATED  TO  THE  SOLICITATION  OF  PROXIES  BY  CARL C. ICAHN, DR. ALEXANDER J.
DENNER,  DR.  THOMAS  F. DEUEL, DR. ERIC ROWINSKY, PROFESSOR RICHARD YOUNG, HIGH
RIVER  LIMITED  PARTNERSHIP,  HOPPER  INVESTMENTS  LLC,  BARBERRY  CORP.,  ICAHN
PARTNERS  LP,  ICAHN  PARTNERS MASTER FUND LP, ICAHN PARTNERS MASTER FUND II LP,
ICAHN  PARTNERS  MASTER  FUND  III  LP,  ICAHN  ENTERPRISES  G.P.  INC.,  ICAHN
ENTERPRISES  HOLDINGS  L.P.,  IPH  GP LLC, ICAHN CAPITAL L.P., ICAHN ONSHORE LP,
ICAHN  OFFSHORE  LP,  BECKTON  CORP., AND CERTAIN OF THEIR RESPECTIVE AFFILIATES
FROM  THE  STOCKHOLDERS  OF BIOGEN IDEC INC., FOR USE AT ITS ANNUAL MEETING WHEN
AND  IF  THEY BECOME AVAILABLE, BECAUSE THEY WILL CONTAIN IMPORTANT INFORMATION,
INCLUDING  INFORMATION  RELATING  TO  THE  PARTICIPANTS  IN  ANY  SUCH  PROXY
SOLICITATION.  WHEN AND IF COMPLETED, A DEFINITIVE PROXY STATEMENT AND A FORM OF
PROXY  WILL  BE  AVAILABLE  TO  STOCKHOLDERS  OF  BIOGEN  IDEC  INC.  FROM  THE
PARTICIPANTS  AT  NO  CHARGE  AND  WILL  ALSO  BE  AVAILABLE AT NO CHARGE AT THE
SECURITIES  AND  EXCHANGE  COMMISSION'S  WEBSITE  AT  HTTP://WWW.SEC.GOV.

INFORMATION RELATING TO THE PARTICIPANTS IN THIS PROXY SOLICITATION IS CONTAINED
IN  SCHEDULE  14A  FILED  BY  MR.  ICAHN  AND CERTAIN OF HIS AFFILIATES WITH THE
SECURITIES  AND  EXCHANGE  COMMISSION  ON  JANUARY  28,  2010, WHICH DOCUMENT IS
AVAILABLE  AT  NO  CHARGE AT THE SECURITIES AND EXCHANGE COMMISSION'S WEBSITE AT
HTTP://WWW.SEC.GOV.

Item 7. Materials to Be Filed as Exhibits.

Item 7 is hereby amended by the addition of the following:

Exhibit 1.   Stockholders' Notice of  Nomination  of  Persons  for  Election  as
             Directors  and  Other  Proposed  Business  at  the  2010  Annual
             Meeting of Stockholders  of  Biogen  Idec  Inc.



                                   SIGNATURE

     After  reasonable  inquiry  and  to  the  best  of  each of the undersigned
knowledge and belief, each of the undersigned certifies that the information set
forth  in  this  statement  is  true,  complete  and  correct.

Dated:  January  27,  2010


HOPPER  INVESTMENTS  LLC
BARBERRY  CORP.
ICAHN  PARTNERS  MASTER  FUND  LP
ICAHN  PARTNERS  MASTER  FUND  II  LP
ICAHN  PARTNERS  MASTER  FUND  III  LP
ICAHN  OFFSHORE  LP
ICAHN  PARTNERS  LP
ICAHN  ONSHORE  LP
BECKTON  CORP.


HIGH  RIVER  LIMITED  PARTNERSHIP
     By:  Hopper  Investments  LLC,  general  partner

     By:  /s/  Edward E. Mattner
          ----------------------
          Name:  Edward  Mattner
          Title:  Authorized  Signatory


ICAHN  CAPITAL  LP
     By:  IPH  GP  LLC,  its  general  partner
     By:  Icahn  Enterprises  Holdings  L.P.,  its  sole  member
     By:  Icahn  Enterprises  G.P.  Inc.,  its  general  partner

     By:  /s/Dominick  Ragone
          -------------------
          Name:  Dominick  Ragone
          Title:  Chief  Financial  Officer


IPH  GP  LLC
     By:  Icahn  Enterprises  Holdings  L.P.,  its  sole  member
     By:  Icahn  Enterprises  G.P.  Inc.,  its  general  partner

     By:  /s/Dominick  Ragone
          -------------------
          Name:  Dominick  Ragone
          Title:  Chief  Financial  Officer


ICAHN  ENTERPRISES  HOLDINGS  L.P.
     By:  Icahn  Enterprises  G.P.  Inc.,  its  general  partner

     By:  /s/Dominick  Ragone
          -------------------
          Name:  Dominick  Ragone
          Title:  Chief  Financial  Officer


ICAHN  ENTERPRISES  G.P.  INC.

     By:  /s/Dominick  Ragone
          -------------------
          Name:  Dominick  Ragone
          Title:  Chief  Financial  Officer


/s/  Carl  C.  Icahn
--------------------
CARL  C.  ICAHN






      [Signature Page of Schedule 13D, Amendment No. 2 - Biogen Idec Inc.]




                                                                       EXHIBIT I

                               ICAHN PARTNERS LP
                         ICAHN PARTNERS MASTER FUND LP
                        ICAHN PARTNERS MASTER FUND II LP
                       ICAHN PARTNERS MASTER FUND III LP
                         HIGH RIVER LIMITED PARTNERSHIP
                        c/o Icahn Capital Management LP
                          767 Fifth Avenue, 47th Floor
                               New York, NY 10153

January  27,  2010

VIA HAND DELIVERY, EMAIL AND FACSIMILE
--------------------------------------
Biogen  Idec  Inc.
14  Cambridge  Center
Cambridge,  Massachusetts  02142
Attention:  James  C.  Mullen,  Chief  Executive  Officer
            Susan  H.  Alexander,  General  Counsel  and  Secretary

Re:  Stockholders' Notice (this "Notice") of Nomination of Persons for Election
     Directors and Other Proposed Business at the 2010 Annual Meeting of
     Stockholders of Biogen Idec Inc. (the "Corporation")
     --------------------------------------------------------------------------

Ladies and Gentlemen:

     Icahn Partners LP, a Delaware limited partnership ("Icahn Partners"), Icahn
Partners  Master  Fund LP, a Cayman Islands exempted limited partnership ("Icahn
Master"),  Icahn  Partners  Master Fund II LP, a Cayman Islands exempted limited
partnership  ("Icahn  Master  II"),  Icahn Partners Master Fund III LP, a Cayman
Islands exempted limited partnership ("Icahn Master III") and High River Limited
Partnership,  a  Delaware  limited  partnership ("High River", and together with
Icahn  Partners, Icahn Master, Icahn Master II and Icahn Master III, the "Record
Holders"  and  each  of  them a "Record Holder") hereby submit this notice (this
"Notice")  on  the  date  hereof  pursuant  to  the  requirements  (the  "Bylaw
Requirements")  of  the  Second  Amended and Restated Bylaws of the Corporation,
adopted  as of October 13, 2008 and amended as of June 3, 2009 (the "Bylaws") of
their  intent  (i)  to  nominate  the  Slate  (as defined below) for election as
directors  of  the Corporation at the 2010 annual meeting of stockholders of the
Corporation  (the "Annual Meeting"), or a special meeting of stockholders of the
Corporation  called  for a similar purpose, and as a separate matter and (ii) to
propose certain amendments to the Bylaws. This Notice is submitted by the Record
Holders  and  on  behalf  of  the  Beneficial  Owners  (as  defined in Annex A).

     The address of Icahn Partners is 767 Fifth Avenue, 47th Floor, New York, NY
10153.  The  address of Icahn Master is c/o Walkers SPV Limited, P.O. Box 908GT,
87  Mary Street, George Town, Grand Cayman, Cayman Islands. The address of Icahn
Master II is c/o Walkers SPV Limited, Walker House, 87 Mary Street, George Town,
Grand  Cayman  KY1-9002,  Cayman Islands. The address of Icahn Master III is c/o
Walkers  SPV  Limited,  Walker  House, 87 Mary Street, George Town, Grand Cayman
KY1-9002,  Cayman  Islands  (1).  The address of High River is 767 Fifth Avenue,
47th  Floor,  New  York,  NY 10153. Each of Icahn Master, Icahn Master II, Icahn
Master  III,  Icahn Partners and High River is primarily engaged in the business
of  investing  in  securities.

     As  of  the  close  of  business on January 26, 2010 (i) each of the Record
Holders  represents  that  it  is  the holder of record of 1000 shares of Common
Stock,  par  value  $0.0005  per  share, of the Corporation (the "Shares"); (ii)
Icahn  Partners  represents  that it is the direct beneficial owner of 4,532,847
Shares  (including the 1000 Shares of which Icahn Partners is the stockholder of
record); (iii) Icahn Master represents that it is the direct beneficial owner of
5,888,807  Shares  (including  the  1000  Shares  of  which  Icahn Master is the
stockholder  of  record);  (iv) Icahn Master II represents that it is the direct
beneficial  owner  of 1,761,077 Shares (including the 1000 Shares of which Icahn
Master II is the stockholder of record); (v) Icahn Master III represents that it
is  the  direct beneficial owner of 677,474 Shares (including the 1000 Shares of
which  Icahn  Master  III  is  the  stockholder  of record); and (vi) High River
represents that it is the direct beneficial owner of 3,215,051 Shares (including
the  1000 Shares of which High River is the stockholder of record), in each case
as  further described in Annex A. Carl C. Icahn by virtue of his relationship to
Icahn  Partners,  Icahn Master, Icahn Master II, Icahn Master III and High River
is  deemed  to  beneficially  own  (as that term is defined in Rule 13d-3 of the
Securities  Act  of  1933,  as  amended)  the Shares which Icahn Partners, Icahn
Master,  Icahn  Master II, Icahn Master III and High River directly beneficially
own,  as  further  described  in  Annex  A.
_________________________
(1)  Please  note  that  the  following  address  is  set  forth  on  the  stock
     certificate of each of Icahn Partners, Icahn Master, Icahn Master II, Icahn
     Master  III  and  High  River  as  its  record  address on the books of the
     Corporation:  c/o Icahn Associates Corp., 767 Fifth Avenue, 47th Floor, New
     York,  New  York  10153.



     Each of the Record Holders and the Beneficial Owners hereby represents that
each  Record  Holder and Beneficial Owner will notify the Corporation in writing
of  the class, series and number of such Shares owned beneficially and of record
as  of  the  record  date  for  the  Annual Meeting (the "Record Date") promptly
following  the later of the Record Date or the date notice of the Record Date is
first  publicly  disclosed,  however, such representation is not an admission by
any  Record  Holder,  Nominee  or  Beneficial  Owner  or any of their respective
affiliates  of  the  legality  thereof  or  that  such notification is required.

     Other  than  as  disclosed  in  Annex  A,  each  of  the Record Holders and
Beneficial  Owners  hereby  represents  that  it  does  not  own  any Derivative
Instruments  (as  defined  in  the  Bylaws)  or  any  other  direct  or indirect
opportunity  to  profit  or  share  in  any  profit derived from any increase or
decrease  in  the  value  of  the  Shares.  Each  of  the Record Holders and the
Beneficial Owners hereby represents that each Record Holder and Beneficial Owner
will  notify  the  Corporation  in  writing of any such Derivative Instrument in
effect  as of the Record Date promptly following the later of the Record Date or
the  date  notice  of the Record Date is first publicly disclosed, however, such
representation  is  not an admission by any Record Holder, Nominee or Beneficial
Owner or any of their respective affiliates of the legality thereof or that such
notification  is  required.

     Each Record Holder hereby represents that it intends to appear in person or
by  proxy at the Annual Meeting to nominate for election as class I directors of
the  Corporation  the following persons (each, a "Nominee" and collectively, the
"Slate"):

                              Dr. Thomas F. Deuel
                               Dr. Eric Rowinsky
                           Professor Richard A. Young

     Dr.  Deuel  and  Dr.  Rowinsky  are highly accomplished clinical experts in
cancer  and  Professor  Young  is  a  pioneer  in gene transcription. The Record
Holders  believe  that  these  experts  knowledge  of  science and medicine will
significantly  improve  the  clinical  and  scientific expertise of the Board of
Directors.  We  also  believe that each nominee is a strong shareholder-oriented
individual  who  will  help  represent  the  best interests of the Corporation's
shareholders.

     As  a  separate  matter,  in  order to restrict the ability of the Board of
Directors  to  increase  the  size  of  the  Board,  each  Record  Holder hereby
represents that it intends to appear in person or by proxy at the Annual Meeting
to  propose certain amendments to the Bylaws (the "Bylaw Amendments") that would
fix  the  number  of  directors  at  twelve  (12).

     The  Bylaw  Amendments are a proper matter for stockholder action under the
General  Corporation  Law  of Delaware. The Record Holders believe that it is in
the  best  interests  of the Corporation's stockholders to limit the size of the
Board  of  Directors  to  twelve  (12) directors. The Bylaws currently allow the
Board  of  Directors  to  increase  the  size  of the board at any time in their
discretion.  Furthermore,  vacancies  resulting  from such increases may only be
filled  by  the  Board  of  Directors.  The  Record  Holders  believe  that  the
shareholders  of  the  Corporation  should  know  with certainty the size of the
Board.

     The proposal states:

     "RESOLVED, that the Bylaws be and hereby are amended as follows:

     -    To replace  the  first  sentence  of  Section 3.1 in its entirety with
          the  following  sentence:

          "The  number  of  directors  that  shall  constitute  the entire Board
          shall  be  twelve  (12)."

     -    To  delete  the  first  sentence  of  Section  3.2  in  its  entirety.

     -    To delete  the  words  "and  newly  created  directorships  resulting
          from any increase in the authorized number of directors", appearing in
          the  second  sentence  of  Section  3.2  in  their  entirety."

     In  this Notice: (i) certain information relating to the Record Holders and
Beneficial  Owners  is  set  forth  in  the  body  of this Notice (including the
footnotes hereto) and Annex A; (ii) certain information relating to each Nominee
is  set  forth in the body of this Notice and Annex B; (iii) the written consent
of  each  Nominee  to  being  named  in  the proxy statement as a nominee and to
serving  as a director of the Corporation if elected is attached as Annex C; and
(iv) each Nominee has executed a copy of the Director Nominee Representation and
Agreement attached as Annex D. Each Nominee is also party to a nominee agreement
with  the  Record  Holders substantially in the form attached hereto as Annex E,
pursuant  to  which  the  Record Holders have agreed to pay certain fees to each
Nominee  and to indemnify each Nominee with respect to certain costs incurred by
each Nominee in connection with the proxy contest relating to the Annual Meeting
(the  "Nominee  Agreement"). In connection with the Record Holders proxy contest
against the Corporation in 2009, Dr. Deuel also entered into a nominee agreement
substantially  in  the form attached hereto as Annex E and was paid certain fees
by  the Record Holders in 2009 in connection with his nomination to the board of
directors  of  the  Corporation.

     Each  Nominee,  Record  Holder  and Beneficial Owner has an interest in the
election  of  directors  at  the  Annual Meeting: (i) directly and/or indirectly
through  the  beneficial  ownership  (if  any)  of  Shares,  as described on the
applicable  attachment to Annex A and (ii) pursuant to the Nominee Agreement, if
applicable,  relating  to  such  Nominee  and  each  Record  Holder.

     Other  than  as  disclosed  in this Notice, none of the Record Holders, the
Beneficial  Owners,  or any of their respective affiliates or associates, or any
others  acting  in  concert  with  any  of  the  foregoing  have  any agreement,
arrangement  or  understanding with respect to the nomination of the Nominees or
the  Bylaw Amendments. Each Record Holder and Beneficial Owner hereby represents
that  it  will  notify  the  Corporation  in  writing  of  any  such agreements,
arrangements  or  understandings  in  effect  as  of  the  Record  Date promptly
following  the later of the Record Date or the date notice of the Record Date is
first  publicly  disclosed.

     With  respect  to each Nominee, other than as disclosed in this Notice, (i)
such  Nominee  is  not,  nor  was within the past year, a party to any contract,
arrangement  or  understanding with any person with respect to any securities of
the  Corporation,  including, but not limited to, joint ventures, loan or option
arrangements,  puts  or  calls, guarantees against loss or guarantees of profit,
division of losses or profits, or the giving or withholding of proxies; and (ii)
neither  such  Nominee nor any of such Nominee's associates have any arrangement
or  understanding  with  any person with respect to (A) any future employment by
the  Corporation  or  its affiliates or (B) any future transactions to which the
Corporation  or  any  of  its  affiliates  will  or  may  be  a  party.

     With  respect  to  each  Record  Holder and Beneficial Owner, other than as
disclosed  in  this  Notice,  (i) neither such Record Holder nor such Beneficial
Owner is, nor was, within the past year, a party to any contract, arrangement or
understanding with any person with respect to any securities of the Corporation,
including, but not limited to, joint ventures, loan or option arrangements, puts
or calls, guarantees against loss or guarantees of profit, division of losses or
profits,  or  the giving or withholding of proxies; and (ii) neither such Record
Holder,  Beneficial  Owner  nor  any  of  their  respective  associates have any
arrangement  or  understanding  with  any  person with respect to (A) any future
employment  by  the Corporation or its affiliates or (B) any future transactions
to  which  the  Corporation  or  any  of  its affiliates will or may be a party.

     With  respect  to  each  Nominee,  such  Nominee  is  independent under the
independence  standards  applicable to the Corporation under paragraph (a)(1) of
Item  407  of  Regulation  S-K.

     In  response  to  the Bylaw Requirements, the legality of which neither the
Record  Holders  nor  the  Beneficial Owners concede, the Record Holders and the
Beneficial Owners state their intention to deliver a proxy statement and form of
proxy  to  holders  of  at least the percentage of the Corporation's outstanding
capital stock required to adopt the Bylaw Amendments, and a sufficient number of
the  holders  of the Corporation's outstanding capital stock to elect the Slate.
Each  Record  Holder  hereby  represents  that  it intends to solicit proxies in
support of the nomination of the Slate and the adoption of the Bylaw Amendments.

     In  consideration  of providing certain investment advisory, administrative
and  back  office  services to the Record Holders, Icahn Onshore LP, the general
partner  of  Icahn  Partners and Icahn Offshore LP, the general partner of Icahn
Master,  Icahn  Master  II  and  Icahn  Master  III,  (together,  the  "General
Partners"),  receive  from  the  Record  Holders  on an annual basis (i) special
profit  interest  allocations  generally equal to 2.5% of the balance in each of
the  Record  Holders'  capital accounts attributable to fee-paying investors and
(ii)  incentive  allocations generally equal to 25% of the net profits generated
by  fee-paying  investors of the Record Holders. Therefore, the amounts received
by the General Partners will be affected by the combination of fee-paying assets
under management and the investment performance of the Record Holders (including
any increase or decrease in the value of shares of the Corporation). The General
Partners  are  owned  by  Icahn  Capital  LP,  which  is  a  subsidiary of Icahn
Enterprises  L.P.,  a  New York Stock Exchange listed master limited partnership
("Icahn  Enterprises").  Carl  C.  Icahn  is  the  indirect owner of the general
partner  of  Icahn Enterprises and the indirect holder of approximately 92.0% of
the  outstanding  depositary units representing limited partnership interests in
Icahn  Enterprises  and  approximately  86.5%  of  the  preferred units in Icahn
Enterprises.

     The  Annexes  and  all attachments thereto are hereby incorporated into and
made  a  part  of this Notice. Accordingly, all matters disclosed in any part of
this  Notice, including the Annexes and all attachments thereto should be deemed
disclosed for all purposes of this Notice. All upper case terms appearing in the
Annexes  and  all  attachments  thereto that are not defined in such Annexes and
attachments  shall  have  the  meanings  given in the body of this Notice or the
Annexes,  as  applicable.

     Information  is set forth herein as of the close of business on January 26,
2010. Neither the delivery of this Notice nor any delivery by any Record Holder,
Beneficial  Owner,  or Nominee of additional information to the Corporation from
and  after  the  date  hereof  shall be deemed to constitute an admission by any
Record  Holder,  Beneficial Owner, Nominee or any of their respective affiliates
(if  any) that such delivery is required or that each and every item or any item
of information is required or as to the legality or enforceability of any notice
requirement  or  any  other matter, or a waiver by any Record Holder, Beneficial
Owner,  Nominee or any of their respective affiliates (if any) of their right to
contest  or  challenge, in any way, the validity or enforceability of any notice
requirement  or  any  other  matter  (including  actions  taken  by the Board of
Directors  of  the Corporation in anticipation of, or following receipt of, this
Notice). Furthermore, if the Board of Directors of the Corporation increases the
number  of  directors  to  be  nominated  and elected at the Annual Meeting, the
Record  Holders reserve the right to add additional director nominees in respect
of  each  such  additional  directorship.  In  the  event any statement or other
information  in  this  Notice  is  not  correct, or to the extent any applicable
information  has  been  omitted from this Notice, the Record Holders, Beneficial
Owners  and  Nominees  reserve  the  right to correct and/or supplement any such
statement  or  other  information  set  forth  in  this  Notice.

     The  Record Holders have filed a Schedule 13D under the Securities Exchange
Act  of  1934, as amended (the "Exchange Act"), with the Securities and Exchange
Commission  (the  "SEC") relating to the Corporation (the "Filing"). The Filing,
all  attachments  and  any amendments thereto and all future amendments thereto,
are  hereby  incorporated  into  and made a part of this Notice (but only to the
extent  that the information disclosed therein constitutes information regarding
the  Record  Holders,  Beneficial  Owners or Nominees that is required to be set
forth  in this Notice pursuant to the Bylaw Requirements). Accordingly, all such
matters  disclosed in any part of the Filing, including all attachments thereto,
should  be  deemed disclosed for all purposes of this Notice. The Filing, a copy
of  which  was  previously  delivered  to the Corporation pursuant to Rule 13d-7
under  the  Exchange  Act,  is  available  at  no charge at the SEC's website at
http://www.sec.gov. If the Corporation requests additional copies of the Filing,
the  Record  Holders  will  provide  them  and  original signed Director Nominee
Representations  and  Agreements  and  nominee  consents  shall be provided upon
written  request  by  the  Corporation.

                            [Signature page follows]



Very  truly  yours,


ICAHN  PARTNERS  LP


By:  __________________________
     Name:  Edward  E.  Mattner
     Title:  Authorized  Signatory


ICAHN  PARTNERS  MASTER  FUND  LP


By:  __________________________
     Name:  Edward  E.  Mattner
     Title:  Authorized  Signatory


ICAHN  PARTNERS  MASTER  FUND  II  LP


By:  __________________________
     Name:  Edward  E.  Mattner
     Title:  Authorized  Signatory

ICAHN  PARTNERS  MASTER  FUND  III  LP


By:  __________________________
     Name:  Edward  E.  Mattner
     Title:  Authorized  Signatory


HIGH  RIVER  LIMITED  PARTNERSHIP
By:  Hopper  Investments  LLC,  its  general  partner
By:  Barberry  Corp.,  its  sole  member


By:  __________________________
     Name:  Edward  E.  Mattner
     Title:  Authorized  Signatory






   [Signature page to Stockholders' Notice of Intent to Nominate Persons for
      Election as Directors at the 2010 Annual Meeting of Stockholders of
                               Biogen Idec, Inc.]



                                                                         ANNEX A

                 CERTAIN INFORMATION ABOUT BENEFICIAL OWNERSHIP

NAME:                   Carl  C.  Icahn

AGE:                    73

BUSINESS                c/o Icahn Capital LP, 767 Fifth Avenue, 47th Floor
ADDRESS:                New York, NY  10153

Residence               15 West 53rd Street, Penthouse B & C
Address:                New York, NY  10019

PRINCIPAL OCCUPATION    See below
OR  EMPLOYMENT:

CITIZENSHIP:            United  States  of  America


     Mr.  Icahn  has  an  interest  in  the  election of directors at the Annual
Meeting  indirectly through the beneficial ownership of securities, as described
below.

Carl  C.  Icahn  has  served as chairman of the board and a director of Starfire
Holding Corporation ("Starfire"), a privately-held holding company, and chairman
of  the  board  and  a director of various subsidiaries of Starfire, since 1984.
Since  August  2007,  through  his  position as Chief Executive Officer of Icahn
Capital  LP,  a  wholly-owned  subsidiary  of  Icahn  Enterprises  L.P.  ("Icahn
Enterprises"), and certain related entities, Mr. Icahn's principal occupation is
managing  private  investment funds, including Icahn Partners LP, Icahn Partners
Master Fund LP, Icahn Partners Master Fund II LP, and Icahn Partners Master Fund
III  LP.  From November 2004 to August 2007, Mr. Icahn conducted this occupation
through  his  entities  CCI  Onshore Corp. and CCI Offshore Corp. Since November
1990,  Mr.  Icahn has been chairman of the board of Icahn Enterprises G.P. Inc.,
the  general  partner  of  Icahn Enterprises. Icahn Enterprises is a diversified
holding  company  engaged  in  a  variety  of  businesses,  including investment
management,  metals,  automotive,  real estate, railcar, food/packaging and home
fashion. Mr. Icahn was chairman of the board and president of Icahn & Co., Inc.,
a  registered  broker-dealer  and  a  member  of  the  National  Association  of
Securities  Dealers,  from 1968 to 2005. Mr. Icahn has served as chairman of the
board  and as a director of American Railcar Industries, Inc., a company that is
primarily  engaged  in  the  business  of  manufacturing covered hopper and tank
railcars,  since  1994.  From  October  1998 through May 2004, Mr. Icahn was the
president  and a director of Stratosphere Corporation, the owner and operator of
the  Stratosphere Hotel and Casino in Las Vegas, which, until February 2008, was
a  subsidiary  of  Icahn  Enterprises. From September 2000 to February 2007, Mr.
Icahn  served  as the chairman of the board of GB Holdings, Inc., which owned an
interest  in  Atlantic Coast Holdings, Inc., the owner and operator of The Sands
casino  in  Atlantic  City  until November 2006. From September 2006 to November
2008,Mr.  Icahn  was  a  director of ImClone Systems Incorporated ("ImClone"), a
biopharmaceutical  company,  and  from October 2006 to November 2008, he was the
chairman of the board of ImClone. Mr. Icahn has been chairman of the board and a
director  of  XO  Holdings,  Inc., a telecommunications services provider, since
February  2006,  and  of its predecessor from January 2003 to February 2006. Mr.
Icahn  has  served  as a director of Cadus Corporation, a company engaged in the
ownership  and  licensing  of yeast-based drug discovery technologies since July
1993.  In  May 2005, Mr. Icahn became a director of Blockbuster Inc., a provider
of  in-home  movie  rental  and  game  entertainment. In October 2005, Mr. Icahn
became  a  director  of WestPoint International, Inc., a manufacturer of bed and
bath  home fashion products. From August 2007 to September 2009, Mr. Icahn was a
director  of  WCI Communities, Inc. ("WCI"), a homebuilding company. In December
2007,  Mr.  Icahn  became  a  director  of  Federal-Mogul  Corporation
("Federal-Mogul"),  a  supplier  of automotive products, and since January 2008,
has been the chairman of the board of Federal-Mogul. From August 2008 to October
2009,  Mr. Icahn was a director of Yahoo! Inc., a company that provides Internet
services  to  users, advertisers, publishers and developers worldwide. Mr. Icahn
received  his  B.A.  from  Princeton  University.

In  addition, and without acknowledging the following disclosure is required, on
January  5, 2001, Reliance Group Holdings, Inc. ("Reliance") commenced an action
in  the  United  States  District  Court  for  the Southern District of New York
against  Mr.  Icahn,  Icahn  Associates  Corp. and High River alleging that High
River's  tender offer for Reliance 9% senior notes violated Section 14(e) of the
Exchange  Act. Reliance sought a temporary restraining order and preliminary and
permanent injunctive relief to prevent defendants from purchasing the notes. The
Court  initially  imposed  a  temporary  restraining  order.  Defendants  then
supplemented  the tender offer disclosures. The Court conducted a hearing on the
disclosures  and  other  matters  raised by Reliance. It then denied plaintiff's
motion  for  a  preliminary  injunction and ordered dissolution of its temporary
restraining  order  following  dissemination of the supplement. Reliance took an
immediate  appeal  to  the United States Court of Appeals for the Second Circuit
and  sought  a  stay  to  restrain  defendants  from purchasing notes during the
pendency  of  the  appeal.  On  January  30,  2001,  the Court of Appeals denied
plaintiff's  stay  application.  On  January  30, Reliance also sought a further
temporary  restraining  order  from the District Court. The Court considered the
matter  and  reimposed  its original restraint until noon the next day, at which
time the restraint was dissolved. The appeal was argued on March 9 and denied on
March  22,  2001.




                   BENEFICIAL OWNERSHIP OF SECURITIES OF THE
                   CORPORATION AS OF THE DATE OF THIS NOTICE:


(1) Title of     (2) Name of             (3) Amount of           (4) Percent of
    Class            Beneficial              Beneficial              Class (3)
                     Owner (2)               Ownership

Common Stock,        High River               3,215,051               1.10%
par value $0.0005
per share
"Shares")

Shares               Icahn Partners           4,532,847               1.55%

Shares               Icahn Master             5,888,807               2.02%

Shares               Icahn Master II          1,761,077               0.60%

Shares               Icahn Master III           677,474               0.23%

_________________________
(2)  Please note that each Record Holder listed in this table is, as of the date
     of  this  Notice, the direct beneficial owner of the Shares set forth under
     the  heading  "(3)  Amount  of  Beneficial  Ownership"  and  that  indirect
     beneficial ownership of Shares is described below in the text of this Annex
     A  under  the  heading  "Description  of  Beneficial  Ownership.

(3)  Please  note  that  percentages  of ownership set forth in this column were
     calculated  based  on  the  number of Shares stated to be outstanding as of
     October  14,  2009  by the Corporation in the Corporation's Form 10-Q filed
     for  the  quarterly  period  ended  September  30,  2009




           DESCRIPTION OF BENEFICIAL OWNERSHIP AND BENEFICIAL OWNERS

     Barberry  Corp., a Delaware corporation ("Barberry"), is the sole member of
Hopper  Investments  LLC, a Delaware limited liability company ("Hopper"), which
is  the  general  partner  of  High River. Beckton Corp., a Delaware corporation
("Beckton")  is  the sole stockholder of Icahn Enterprises G.P. Inc., a Delaware
corporation  ("Icahn  Enterprises  GP"),  which  is the general partner of Icahn
Enterprises  Holdings  L.P.,  a Delaware limited partnership ("Icahn Holdings").
Icahn  Holdings  is  the sole member of IPH GP LLC, a Delaware limited liability
company  ("IPH"), which is the general partner of Icahn Capital L.P., a Delaware
limited  partnership  ("Icahn Capital"). Icahn Capital is the general partner of
each  of  Icahn Onshore LP, a Delaware limited partnership ("Icahn Onshore") and
Icahn  Offshore  LP,  a  Delaware  limited partnership ("Icahn Offshore"). Icahn
Onshore  is the general partner of Icahn Partners. Icahn Offshore is the general
partner  of  each of Icahn Master, Icahn Master II and Icahn Master III. Each of
Barberry  and  Beckton  is  100 percent owned by Carl C. Icahn ("Mr. Icahn," and
collectively  with  Barberry,  Hopper,  Beckton,  Icahn  Enterprises  GP,  Icahn
Holdings,  IPH,  Icahn  Capital,  Icahn Onshore, Icahn Offshore, the "Beneficial
Owners"  and  each  of  them  a  "Beneficial  Owner." As such, Mr. Icahn is in a
position  indirectly  to  determine  the investment and voting decisions made by
each  of  the  Record  Holders.

     The  principal  business  address  of  each  of  (i)  Icahn Offshore, Icahn
Onshore, Icahn Capital, IPH, Icahn Holdings, Icahn Enterprises GP and Beckton is
White Plains Plaza, 445 Hamilton Avenue - Suite 1210, White Plains, NY 10601 and
(ii)  Mr.  Icahn, Barberry and Hopper is c/o Icahn Capital LP, 767 Fifth Avenue,
47th  Floor,  New  York,  NY  10153.

     Barberry is primarily engaged in the business of serving as the sole member
of  Hopper  and  investing  in  securities.  Hopper  is primarily engaged in the
business  of  serving  as  the  general  partner  of High River and investing in
securities.  Icahn  Offshore  is primarily engaged in the business of serving as
the  general  partner  of each of Icahn Master, Icahn Master II and Icahn Master
III.  Icahn  Onshore  is  primarily  engaged  in  the business of serving as the
general  partner  of  Icahn  Partners. Icahn Capital is primarily engaged in the
business  of  serving as the general partner of each of Icahn Offshore and Icahn
Onshore.  IPH  is  primarily  engaged  in the business of serving as the general
partner of Icahn Capital. Icahn Holdings is primarily engaged in the business of
holding  direct  or  indirect  interests  in various operating businesses. Icahn
Enterprises  GP  is  primarily engaged in the business of serving as the general
partner  of  each  of Icahn Enterprises and Icahn Holdings. Beckton is primarily
engaged  in  the  business of holding the capital stock of Icahn Enterprises GP.

     The  Record Holders and Carl C. Icahn may be deemed to beneficially own, in
the  aggregate,  16,075,256  Shares,  representing  approximately  5.56%  of the
Corporation's outstanding Shares (based upon the 289,198,517 Shares stated to be
outstanding  as of October 14, 2009 by the Corporation in the Corporation's Form
10-Q  filed  for  the  quarterly  period  ended  September  30,  2009).

     High  River has sole voting power and sole dispositive power with regard to
3,215,051 Shares. Each of Hopper, Barberry and Mr. Icahn has shared voting power
and shared dispositive power with regard to such Shares. Icahn Partners has sole
voting power and sole dispositive power with regard to 4,532,847 Shares. Each of
Icahn Onshore, Icahn Capital, IPH, Icahn Holdings, Icahn Enterprises GP, Beckton
and  Mr.  Icahn has shared voting power and shared dispositive power with regard
to  such  Shares.  Icahn Master has sole voting power and sole dispositive power
with  regard  to  5,888,807  Shares. Each of Icahn Offshore, Icahn Capital, IPH,
Icahn  Holdings,  Icahn  Enterprises GP, Beckton and Mr. Icahn has shared voting
power  and  shared dispositive power with regard to such Shares. Icahn Master II
has  sole  voting  power  and  sole  dispositive  power with regard to 1,761,077
Shares.  Each  of  Icahn  Offshore,  Icahn  Capital,  IPH, Icahn Holdings, Icahn
Enterprises  GP,  Beckton  and  Mr.  Icahn  has  shared  voting power and shared
dispositive  power  with regard to such Shares. Icahn Master III has sole voting
power  and  sole  dispositive power with regard to 677,474 Shares. Each of Icahn
Offshore,  Icahn Capital, IPH, Icahn Holdings, Icahn Enterprises GP, Beckton and
Mr.  Icahn  has  shared voting power and shared dispositive power with regard to
such  Shares.

     Each of Hopper, Barberry and Mr. Icahn, by virtue of their relationships to
High  River,  may  be deemed to indirectly beneficially own the 3,215,051 Shares
which  High  River  directly  beneficially  owns.  Each  of Icahn Onshore, Icahn
Capital,  IPH,  Icahn  Holdings, Icahn Enterprises GP, Beckton and Mr. Icahn, by
virtue  of  their  relationships  to Icahn Partners, may be deemed to indirectly
beneficially own the 4,532,847 Shares which Icahn Partners directly beneficially
owns.  Each  of  Icahn  Offshore,  Icahn  Capital,  IPH,  Icahn  Holdings, Icahn
Enterprises GP, Beckton and Mr. Icahn, by virtue of their relationships to Icahn
Master,  Icahn  Master  II  and  Icahn  Master  III, may be deemed to indirectly
beneficially  own  the  8,327,358 Shares which Icahn Master, Icahn Master II and
Icahn  Master  III  directly  beneficially  own.

TWO YEAR SUMMARY TABLE:

The  following  table indicates the date of each purchase and sale of Shares, as
well  as  the  exercise  of  any  call  options,  if  any,  by Mr. Icahn and his
affiliates  within  the  past  two  years, and the number of shares in each such
purchase  and  sale.



NAME                     DATE                              SHARES PURCHASED/SOLD
----                     ----                              ---------------------
HIGH RIVER

High River            January 24, 2008                              33,000
High River            January 25, 2008                             390,000
High River              August 1, 2008                             180,000
High River              August 1, 2008                             541,600
High River              August 4, 2008                             100,000
High River              August 5, 2008                               4,900
High River              August 6, 2008                              39,280
High River              August 7, 2008                              50,000
High River              August 8, 2008                               7,680
High River             August 11, 2008                                 620
High River             August 11, 2008                              91,000
High River            October 28, 2008                            (340,000)
High River            October 29, 2008                            (225,000)
High River            December 2, 2008                              54,300
High River            December 3, 2008                              62,133
High River            December 4, 2008                             131,153
High River            December 5, 2008                              30,204

ICAHN PARTNERS

Icahn Partners        January 24, 2008                              34,982
Icahn Partners        January 25, 2008                             585,855
Icahn Partners          August 1, 2008                             287,915
Icahn Partners          August 1, 2008                           1,108,403
Icahn Partners          August 4, 2008                             159,953
Icahn Partners          August 5, 2008                               7,013
Icahn Partners          August 6, 2008                              62,819
Icahn Partners          August 7, 2008                              79,965
Icahn Partners          August 8, 2008                              12,282
Icahn Partners         August 11, 2008                                 992
Icahn Partners         August 11, 2008                             145,534
Icahn Partners        October 28, 2008                            (866,819)
Icahn Partners        October 29, 2008                            (336,851)
Icahn Partners        December 4, 2008                              92,838
Icahn Partners        December 5, 2008                              42,583

ICAHN MASTER

Icahn Master          January 24, 2008                              85,509
Icahn Master          January 25, 2008                             677,871
Icahn Master            August 1, 2008                             293,286
Icahn Master            August 1, 2008                             611,947
Icahn Master            August 4, 2008                             162,937
Icahn Master            August 5, 2008                               9,307
Icahn Master            August 6, 2008                              64,018
Icahn Master            August 7, 2008                              81,488
Icahn Master            August 8, 2008                              12,518
Icahn Master           August 11, 2008                               1,010
Icahn Master           August 11, 2008                             148,309
Icahn Master          October 28, 2008                            (259,138)
Icahn Master          October 29, 2008                            (387,686)
Icahn Master          December 2, 2008                             217,200
Icahn Master          December 3, 2008                             244,430
Icahn Master          December 4, 2008                             310,807
Icahn Master          December 5, 2008                              55,323

ICAHN MASTER II

Icahn Master II       January 24, 2008                               7,764
Icahn Master II       January 25, 2008                             214,839
Icahn Master II         August 1, 2008                             100,573
Icahn Master II         August 1, 2008                             322,181
Icahn Master II         August 4, 2008                              55,873
Icahn Master II         August 5, 2008                               2,419
Icahn Master II         August 6, 2008                              21,943
Icahn Master II         August 7, 2008                              27,932
Icahn Master II         August 8, 2008                               4,291
Icahn Master II        August 11, 2008                                 346
Icahn Master II        August 11, 2008                              50,836
Icahn Master II       October 28, 2008                            (170,073)
Icahn Master II       October 29, 2008                            (127,108)
Icahn Master II       December 4, 2008                              85,212
Icahn Master II       December 5, 2008                              16,545

ICAHN MASTER III

Icahn Master III      January 24, 2008                               3,745
Icahn Master III      January 25, 2008                              81,435
Icahn Master III        August 1, 2008                              38,226
Icahn Master III        August 1, 2008                             123,869
Icahn Master III        August 4, 2008                              21,237
Icahn Master III        August 5, 2008                                 861
Icahn Master III        August 6, 2008                               8,340
Icahn Master III        August 7, 2008                              10,615
Icahn Master III        August 8, 2008                               1,629
Icahn Master III       August 11, 2008                                 132
Icahn Master III       August 11, 2008                              19,321
Icahn Master III      October 28, 2008                             (63,970)
Icahn Master III      October 29, 2008                             (48,355)
Icahn Master III      December 3, 2008                               4,103
Icahn Master III      December 4, 2008                              35,757
Icahn Master III      December 5, 2008                               6,364


Shares purchased by each of the Record Holders are maintained in margin accounts
that  include  positions  in securities in addition to the Shares. As of January
26,  2010,  the  indebtedness of the margin account of each of High River, Icahn
Partners,  Icahn  Master, Icahn Master II and Icahn Master III was approximately
$402.4  million,  $25.4  million,  $147.0  million,  $4.6  million,  and  zero,
respectively.



                                                                         ANNEX B
                                                                    ATTACHMENT 1

Information about Nominees

NAME:                     Richard A. Young, PhD

AGE:                      55

BUSINESS                  Whitehead Institute for Biomedical Research
ADDRESS:                  Nine Cambridge Center
                          Cambridge, MA  02142

RESIDENCE                 261 Highland Street
ADDRESS:                  Weston, MA 02493

PRINCIPAL OCCUPATION      See below
OR EMPLOYMENT:

CITIZENSHIP:              United States of America

Dr.  Young  does not own, beneficially or of record, any shares of capital stock
of  the  Corporation.  Dr. Young has an interest in the election of directors at
the Annual Meeting pursuant to the Nominee Agreement attached hereto as Annex E.

Dr.  Young  is a Member of the Whitehead Institute and a Professor of Biology at
MIT.  He  received  his B.S. degree in Biological Sciences at Indiana University
and  his  Ph.D. in Molecular Biophysics and Biochemistry at Yale University. Dr.
Young  received  postdoctoral  training  at the Swiss Institute for Experimental
Cancer  Research  and  at  Stanford  University  School  of Medicine. His honors
include  a  Burroughs Wellcome Scholarship, the Chiron Corporation Biotechnology
Research  Award,  Yale's  Wilbur Cross Medal, and Scientific American recognized
him  as  one  of the top 50 leaders in science, technology and business in 2006.
Dr.  Young  has  been associated with a number of biotechnology, pharmaceuticals
and  other  companies, including MedImmune (as member of the Scientific Advisory
Board),  Boehringer  Mannheim  (as  Advisor  to  Board),  Becton  Dickenson  (as
Consultant),  Cubist  Pharmaceuticals  (as  member  of  the  Scientific Advisory
Board),  StressGen  (as  member  of  the  Scientific Advisory Board and Board of
Directors),  Neogenesis  (as founder and member of the Scientific Advisory Board
and  Board  of  Directors;  acquired  by Schering-Plough), Computational Biology
Corporation (as founder and member of the Scientific Advisory Board and Board of
Directors;  acquired  by  Agilent),  Agilent  (as Consultant), Corning, Inc. (as
Consultant)  and  Novartis  (as Ad Hoc member of the Scientific Advisory Board).
Dr.  Young  has  also  served  as  an  advisor to Science magazine, the National
Institutes  of  Health  and  the  World  Health  Organization.



                                                                         ANNEX B
                                                                    ATTACHMENT 3

Information about Nominees

NAME:                     Thomas F. Deuel, M.D.

AGE:                      74

BUSINESS                  The Scripps Research Institute, MEM 268
ADDRESS:                  10550 North Torrey Pines Road
                          La Jolla, CA  92037

RESIDENCE                 2123 De Mayo Road
ADDRESS:                  Del Mar, CA  92014

PRINCIPAL OCCUPATION      See below
OR EMPLOYMENT:

CITIZENSHIP:              United States of America


Dr.  Deuel  does not own, beneficially or of record, any shares of capital stock
of  the  Corporation.  Dr. Deuel has an interest in the election of directors at
the Annual Meeting pursuant to the Nominee Agreement attached hereto as Annex E.

Since  February  2002,  Thomas  F.  Deuel,  M.D.,  has  served as a Professor of
Molecular  and  Experimental Medicine and Cell Biology, Director of the Division
of  Molecular  Oncology,  Department of Molecular and Experimental Medicine, and
Director  of  the  Vascular  Biology  Affinity  Group  at  The  Scripps Research
Institute.  Also, since 1998, Dr. Deuel has served as a Professor of Medicine at
Harvard  Medical School. He is currently a Professor Emeritus at Harvard Medical
School. In addition, from 1996 to 2002, Dr. Deuel served as a Director, Division
of  Growth  Regulation at Beth Israel Hospital, Boston, Massachusetts and, prior
to  that,  was a Professor of Medicine and Biochemistry and the head of Oncology
Services  at  the Washington University School of Medicine, St. Louis, Missouri.
He is a member of the Institute of Medicine at the National Academy of Sciences.
Dr. Deuel is also President of the Edward R. Mallinckrodt Foundation, St. Louis,
Missouri.  He  has  served on various editorial boards, including the Journal of
Clinical  Investigation  and  Blood,  and currently is on the Editorial Board of
Current Opinion in Hematology and Section Editor for Vascular Biology. Dr. Deuel
has  served  and  continues  to serve on numerous scientific advisory boards for
various  companies,  including  scientific  advisory  board  of  Imclone Systems
Incorporated,  a publicly traded biopharmaceutical company, during the existence
of  such  board  (from 1988 to 2001). From July 2007 to December 2008, Dr. Deuel
served  on  Imclone's board of directors. Dr. Deuel has earned many professional
honors  and  awards  and holds an M.D. from Columbia University and an A.B. from
Princeton  University.





                                                                         ANNEX B
                                                                    ATTACHMENT 3

Information about Nominees

NAME:                     Dr. Eric Rowinsky

AGE:                      53

BUSINESS                  5 Robin Road
ADDRESS:                  Warren, NJ 07059

RESIDENCE                 5 Robin Road
ADDRESS:                  Warren, NJ 07059

PRINCIPAL OCCUPATION      See below
OR EMPLOYMENT:

CITIZENSHIP:              United States of America

Dr.  Rowinsky  does  not  own,  beneficially or of record, any shares of capital
stock  of  the  Corporation.  Dr.  Rowinsky  has  an interest in the election of
directors  at  the  Annual  Meeting  pursuant  to the Nominee Agreement attached
hereto  as  Annex  E.

Dr.  Rowinsky  is  currently  a  scientific  consultant  for companies including
ImClone Systems, RRD International, and Champions Biotech. He is also an Adjunct
Professor  of  Medicine  at  New York University. From February 2005 to December
2009, Dr. Rowinsky was the Chief Medical Officer and Executive Vice President of
ImClone  Systems  Incorporated,  and  was  a  director  of  ImClone Systems from
February  2005  to  November 2008. Dr. Rowinsky held the position of Director of
the  Institute  of  Drug  Development  (IDD)  at the Cancer Therapy and Research
Center  from  2002  to 2004 and was the Director of Clinical Research at the IDD
from  1996  to  2002.  In addition, he held the SBC Endowed Chair for Early Drug
Development  at  the  IDD.  From  1996  to 2006, Dr Rowinsky was also a Clinical
Professor  of  Medicine  at  the  University of Texas Health Science Center, San
Antonio,  Texas.  Dr. Rowinsky also served as an Associate Professor of Oncology
at  the  Johns  Hopkins  University School of Medicine from 1988 until 1996. His
focus  is  cancer  drug  development  and  has  played  integral  roles  in  the
development  and  approval  of  a  large  number  of  chemotherapy  and targeted
therapeutics  including paclitaxel, docetaxel, irinotecan, topotecan, erlotinib,
gefitinib,  cetuximab, and temsirolimus among others. He currently serves on the
Board  of  Directors of Adventrx Pharmaceuticals and has served as a director at
Tapestry  Pharmaceuticals.  Dr.  Rowinsky  has  also  served  on  the  Board  of
Scientific  Counselors  of  the National Cancer Institute from 2004 to 2007. Dr.
Rowinsky received a B.A. degree from New York University and an M.D. degree from
the  Vanderbilt  University  School  of  Medicine.  Following  his  residency in
internal  medicine  at  the  University  of  California, San Diego, he completed
fellowship  training  in medical oncology at the Johns Hopkins University School
of  Medicine.




                                                                         ANNEX C

The  written consent of each Nominee to being named as a nominee for election as
a  director of the Corporation and to serve as a director if elected is attached
to  this  Annex  C.  If  the  Corporation requests original signed statements of
consents,  the  Record  Holders  will  provide  them.




                                                                         ANNEX C
                                                                    ATTACHMENT 1

                               CONSENT OF NOMINEE

     The undersigned hereby consents to being named as a nominee for election as
a  director  of  Biogen  Idec Inc. (the "Company"), in the proxy statement to be
filed  with  the  Securities  and  Exchange  Commission  and  distributed  to
stockholders  of  the  Company by High River Limited Partnership ("High River"),
Icahn  Partners  LP  ("Icahn  Partners"),  Icahn Partners Master Fund LP ("Icahn
Master"),  Icahn  Partners Master Fund II LP ("Icahn Master II"), Icahn Partners
Master  Fund III LP ("Icahn Master III", and collectively with High River, Icahn
Partners,  Icahn  Master and Icahn Master II, the "Record Holders") and in other
materials  in  connection with the solicitation of proxies by the Record Holders
from  stockholders  of  the  Company  to  be voted at the 2010 annual meeting of
stockholders of the Company and any adjournment thereof, and further consents to
serve  as  a  director  of  the  Company,  if  elected.

Dated: January 24, 2010


                                                           /s/  Eric  Rowinsky
                                                           ---------------------
                                                           Name:  Eric  Rowinsky



                                                                         ANNEX C
                                                                    ATTACHMENT 2


                               CONSENT OF NOMINEE

The  undersigned  hereby  consents to being named as a nominee for election as a
director of Biogen Idec Inc. (the "Company"), in the proxy statement to be filed
with  the  Securities and Exchange Commission and distributed to stockholders of
the  Company by High River Limited Partnership ("High River"), Icahn Partners LP
("Icahn  Partners"),  Icahn  Partners  Master  Fund  LP  ("Icahn Master"), Icahn
Partners  Master  Fund II LP ("Icahn Master II"), Icahn Partners Master Fund III
LP  ("Icahn Master III", and collectively with High River, Icahn Partners, Icahn
Master  and  Icahn  Master  II,  the "Record Holders") and in other materials in
connection  with  the  solicitation  of  proxies  by  the  Record  Holders  from
stockholders  of  the  Company  to  be  voted  at  the  2010  annual  meeting of
stockholders of the Company and any adjournment thereof, and further consents to
serve  as  a  director  of  the  Company,  if  elected.

Dated: January 24, 2010


                                                        /s/ Thomas  F.  Deuel
                                                        ------------------------
                                                        Name:  Thomas  F.  Deuel



                                                                         ANNEX C
                                                                    ATTACHMENT 3

                               CONSENT OF NOMINEE

The  undersigned  hereby  consents to being named as a nominee for election as a
director of Biogen Idec Inc. (the "Company"), in the proxy statement to be filed
with  the  Securities and Exchange Commission and distributed to stockholders of
the  Company by High River Limited Partnership ("High River"), Icahn Partners LP
("Icahn  Partners"),  Icahn  Partners  Master  Fund  LP  ("Icahn Master"), Icahn
Partners  Master  Fund II LP ("Icahn Master II"), Icahn Partners Master Fund III
LP  ("Icahn Master III", and collectively with High River, Icahn Partners, Icahn
Master  and  Icahn  Master  II,  the "Record Holders") and in other materials in
connection  with  the  solicitation  of  proxies  by  the  Record  Holders  from
stockholders  of  the  Company  to  be  voted  at  the  2010  annual  meeting of
stockholders of the Company and any adjournment thereof, and further consents to
serve  as  a  director  of  the  Company,  if  elected.

Dated: January 24, 2010


                                                             /s/ Richard Young
                                                             -------------------
                                                             Name: Richard Young




                                                                         ANNEX D

The  Director  Nominee  Representation  and  Agreement,  executed by each of the
Nominees  is  attached  to  this  Annex  D. If the Corporation requests original
signed  agreements  of  the  Director  Nominee Representation and Agreement, the
Record  Holders  will  provide  them.



                 DIRECTOR NOMINEE REPRESENTATION AND AGREEMENT

Reference  is made to the Second Amended and Restated Bylaws of Biogen Idec Inc.
(the  "Company")  adopted  as  of October 13, 2008 (the "Bylaws"), which require
that,  in  order  to be eligible to be a nominee for election or reelection as a
director  of  the  Company,  a  person  must timely deliver a representation and
agreement  in compliance with the Bylaws (capitalized terms used but not defined
herein  shall  have  the  meanings  ascribed  thereto  in  the  Bylaws).

1.   The undersigned,  in  order  to be eligible to be a nominee for election or
     reelection  as a director of the Company, does hereby represent and warrant
     that  the  undersigned:

     a.   is not  a  party  to  (i)  a  Voting  Commitment  that  has  not  been
          disclosed  to  the  Company  or  (ii) any Voting Commitment that could
          limit  or  interfere  with  the  undersigned's  ability  to comply, if
          elected as a director of the Company, with the undersigned's fiduciary
          duties  under  applicable  law;
     b.   is not  a  party  to  any  agreement,  arrangement  or  understanding
          with  any  person or entity other than the Company with respect to any
          direct  or  indirect compensation, reimbursement or indemnification in
          connection  with  service  or  action  as a director that has not been
          disclosed  to  the  Company;  and
     c.   would be  in  compliance,  in  the  undersigned's  individual capacity
          and  on  behalf  of  any  person  or  entity  on  whose  behalf  the
          undersigned's  nomination  is  being made, if elected as a director of
          the Company, with applicable law and all applicable publicly disclosed
          corporate  governance, conflict of interest, confidentiality and stock
          ownership  and  trading  policies  and  guidelines  of  the  Company,
          including, without limitation, the Company's Code of Business Conduct,
          the  Company's  Corporate  Governance  Principles  and  the  Company's
          Comprehensive  Compliance  Program.

2.   The undersigned does herby further covenant and agree that the undersigned:

     a.   will not  become  a  party  to  (i)  a  Voting Commitment that has not
          been disclosed to the Company or (ii) any Voting Commitment that could
          limit  or  interfere  with  the  undersigned's  ability  to comply, if
          elected as a director of the Company, with the undersigned's fiduciary
          duties  under  applicable  law;

     b.   will not  become  a  party  to  any  agreement,  arrangement  or
          understanding  with  any  person or entity other than the Company with
          respect  to  any  direct  or  indirect  compensation, reimbursement or
          indemnification  in  connection  with  service or action as a director
          that  has  not  been  disclosed  to  the  Company;  and

     c.   will comply,  in  the  undersigned's  individual  capacity  and  on
          behalf  of  any  person  or  entity  on whose behalf the undersigned's
          nomination  is  being  made,  with  applicable  law and all applicable
          publicly  disclosed  corporate  governance,  conflict  of  interest,
          confidentially and stock ownership and trading policies and guidelines
          of  the  Company, including, without limitation, the Company's Code of
          Business  Conduct,  the  Company's Corporate Governance Principles and
          the  Company's  Comprehensive  Compliance  Program.

                  [Remainder of page intentionally left blank]



IN  WITNESS  WHEREOF,  the  undersigned  has duly executed this Director Nominee
Representation  and  Agreement  as  of  the  24th  day  of  January,  2010.


                                                             /s/ Eric Rowinsky
                                                             -------------------
                                                             Name: Eric Rowinsky


                 DIRECTOR NOMINEE REPRESENTATION AND AGREEMENT

Reference  is made to the Second Amended and Restated Bylaws of Biogen Idec Inc.
(the  "Company")  adopted  as  of October 13, 2008 (the "Bylaws"), which require
that,  in  order  to be eligible to be a nominee for election or reelection as a
director  of  the  Company,  a  person  must timely deliver a representation and
agreement  in compliance with the Bylaws (capitalized terms used but not defined
herein  shall  have  the  meanings  ascribed  thereto  in  the  Bylaws).

1.   The undersigned,  in  order  to be eligible to be a nominee for election or
     reelection  as a director of the Company, does hereby represent and warrant
     that  the  undersigned:

     a.   is not  a  party  to  (i)  a  Voting  Commitment  that  has  not  been
          disclosed  to  the  Company  or  (ii) any Voting Commitment that could
          limit  or  interfere  with  the  undersigned's  ability  to comply, if
          elected as a director of the Company, with the undersigned's fiduciary
          duties  under  applicable  law;
     b.   is not  a  party  to  any  agreement,  arrangement  or  understanding
          with  any  person or entity other than the Company with respect to any
          direct  or  indirect compensation, reimbursement or indemnification in
          connection  with  service  or  action  as a director that has not been
          disclosed  to  the  Company;  and
     c.   would be  in  compliance,  in  the  undersigned's  individual capacity
          and  on  behalf  of  any  person  or  entity  on  whose  behalf  the
          undersigned's  nomination  is  being made, if elected as a director of
          the Company, with applicable law and all applicable publicly disclosed
          corporate  governance, conflict of interest, confidentiality and stock
          ownership  and  trading  policies  and  guidelines  of  the  Company,
          including, without limitation, the Company's Code of Business Conduct,
          the  Company's  Corporate  Governance  Principles  and  the  Company's
          Comprehensive  Compliance  Program.

2.   The undersigned does herby further covenant and agree that the undersigned:

     a.   will not  become  a  party  to  (i)  a  Voting Commitment that has not
          been disclosed to the Company or (ii) any Voting Commitment that could
          limit  or  interfere  with  the  undersigned's  ability  to comply, if
          elected as a director of the Company, with the undersigned's fiduciary
          duties  under  applicable  law;
     b.   will not  become  a  party  to  any  agreement,  arrangement  or
          understanding  with  any  person or entity other than the Company with
          respect  to  any  direct  or  indirect  compensation, reimbursement or
          indemnification  in  connection  with  service or action as a director
          that has not been disclosed to the Company; and
     c.   will comply,  in  the  undersigned's  individual  capacity  and  on
          behalf  of  any  person  or  entity  on whose behalf the undersigned's
          nomination  is  being  made,  with  applicable  law and all applicable
          publicly  disclosed  corporate  governance,  conflict  of  interest,
          confidentially and stock ownership and trading policies and guidelines
          of  the  Company, including, without limitation, the Company's Code of
          Business  Conduct,  the  Company's Corporate Governance Principles and
          the  Company's  Comprehensive  Compliance  Program.

                  [Remainder of page intentionally left blank]



IN  WITNESS  WHEREOF,  the  undersigned  has duly executed this Director Nominee
Representation  and  Agreement  as  of  the  24th  day  of  January,  2010.


                                                              /s/ Thomas Deuel
                                                              ------------------
                                                              Name: Thomas Deuel



                 DIRECTOR NOMINEE REPRESENTATION AND AGREEMENT

Reference  is made to the Second Amended and Restated Bylaws of Biogen Idec Inc.
(the  "Company")  adopted  as  of October 13, 2008 (the "Bylaws"), which require
that,  in  order  to be eligible to be a nominee for election or reelection as a
director  of  the  Company,  a  person  must timely deliver a representation and
agreement  in compliance with the Bylaws (capitalized terms used but not defined
herein  shall  have  the  meanings  ascribed  thereto  in  the  Bylaws).

1.   The undersigned,  in  order  to be eligible to be a nominee for election or
     reelection  as a director of the Company, does hereby represent and warrant
     that  the  undersigned:

     a.   is not  a  party  to  (i)  a  Voting  Commitment  that  has  not  been
          disclosed  to  the  Company  or  (ii) any Voting Commitment that could
          limit  or  interfere  with  the  undersigned's  ability  to comply, if
          elected as a director of the Company, with the undersigned's fiduciary
          duties  under  applicable  law;
     b.   is not  a  party  to  any  agreement,  arrangement  or  understanding
          with  any  person or entity other than the Company with respect to any
          direct  or  indirect compensation, reimbursement or indemnification in
          connection  with  service  or  action  as a director that has not been
          disclosed  to  the  Company;  and
     c.   would be  in  compliance,  in  the  undersigned's  individual capacity
          and  on  behalf  of  any  person  or  entity  on  whose  behalf  the
          undersigned's  nomination  is  being made, if elected as a director of
          the Company, with applicable law and all applicable publicly disclosed
          corporate  governance, conflict of interest, confidentiality and stock
          ownership  and  trading  policies  and  guidelines  of  the  Company,
          including, without limitation, the Company's Code of Business Conduct,
          the  Company's  Corporate  Governance  Principles  and  the  Company's
          Comprehensive  Compliance  Program.

2.   The undersigned does herby further covenant and agree that the undersigned:

     a.   will not  become  a  party  to  (i)  a  Voting Commitment that has not
          been disclosed to the Company or (ii) any Voting Commitment that could
          limit  or  interfere  with  the  undersigned's  ability  to comply, if
          elected as a director of the Company, with the undersigned's fiduciary
          duties  under  applicable  law;
     b.   will not  become  a  party  to  any  agreement,  arrangement  or
          understanding  with  any  person or entity other than the Company with
          respect  to  any  direct  or  indirect  compensation, reimbursement or
          indemnification  in  connection  with  service or action as a director
          that  has  not  been  disclosed  to  the  Company;  and
     c.   will comply,  in  the  undersigned's  individual  capacity  and  on
          behalf  of  any  person  or  entity  on whose behalf the undersigned's
          nomination  is  being  made,  with  applicable  law and all applicable
          publicly  disclosed  corporate  governance,  conflict  of  interest,
          confidentially and stock ownership and trading policies and guidelines
          of  the  Company, including, without limitation, the Company's Code of
          Business  Conduct,  the  Company's Corporate Governance Principles and
          the  Company's  Comprehensive  Compliance  Program.

                  [Remainder of page intentionally left blank]



IN  WITNESS  WHEREOF,  the  undersigned  has duly executed this Director Nominee
Representation  and  Agreement  as  of  the  24th  day  of  January,  2010.


                                                             /s/ Richard Young
                                                             -------------------
                                                             Name: Richard Young




                                    ANNEX E

Attached  to  this Annex E is the form of agreement pursuant to which the Record
Holders  have  agreed  to  pay  certain  fees  to certain of the Nominees and to
indemnify  such Nominees with respect to certain costs incurred by such Nominees
in  connection  with  the  proxy  contest  relating  to  the  Annual  Meeting.




                         HIGH RIVER LIMITED PARTNERSHIP
                               ICAHN PARTNERS LP
                         ICAHN PARTNERS MASTER FUND LP
                        ICAHN PARTNERS MASTER FUND II LP
                       ICAHN PARTNERS MASTER FUND III LP

                                January 24, 2010

Dear ___________:


     This will confirm our understanding as follows:

     You agree that you are willing, should we so elect, to become a member of a
slate  of  nominees  (the  "Slate") to stand for election as directors of Biogen
Idec  Inc.  ("Biogen")  in  connection  with  a proxy contest with management of
Biogen  in  respect  of  the  election of directors of Biogen at the 2010 Annual
Meeting of Stockholders of Biogen (the "Annual Meeting"), expected to be held in
the  Spring of 2010, or a special meeting of stockholders of Biogen called for a
similar  purpose  (the  "Proxy  Contest").

     High  River  Limited  Partnership, Icahn Partners LP, Icahn Partners Master
Fund  LP, Icahn Partners Master Fund II LP and Icahn Partners Master Fund III LP
(collectively,  "Icahn"),  agree  to  pay  the  costs  of  the  Proxy  Contest.

     In addition, upon our filing of a preliminary proxy statement with the SEC,
which  indicates  that  Icahn intends to nominate you for election at the Annual
Meeting,  you will be paid $25,000 by Icahn unless you are elected to serve as a
director of Biogen at the Annual Meeting or a special meeting of stockholders of
Biogen  called  for  a similar purpose or in connection with a settlement of the
Proxy  Contest  by  Icahn  and  Biogen,  in  which case you will not receive any
payment from Icahn in connection with the Proxy Contest. Payment to you pursuant
to  this  paragraph, if any, will be made by Icahn, subject to the terms hereof,
upon  the  earliest  of  (i) the certification of the results of the election in
respect  of the Proxy Contest, (ii) the settlement of the Proxy Contest by Icahn
and  Biogen,  or  (iii)  the  withdrawal  of  the  Proxy  Contest  by  Icahn.

     You  understand  that  it  may  be difficult, if not impossible, to replace
nominees  who,  such  as  yourself,  have agreed to serve on the Slate and later
change their minds and determine not to seek election. Accordingly, the Slate is
relying  upon your agreement to seek election. In that connection, you are being
supplied  with  a questionnaire in which you will provide Icahn with information
necessary for Icahn to make appropriate disclosure both to Biogen and for use in
creating the proxy material to be sent to stockholders of Biogen and to be filed
with  the  Securities and Exchange Commission. You have agreed that (i) you will
immediately  complete  and  sign  the  questionnaire  and return it to Andrew N.
Langham,  Assistant  General  Counsel,  Icahn  Enterprises LP, 767 Fifth Avenue,
Suite 4700, New York, NY 10153, Tel: (212) 702-4382, Fax: (212) 688-1158, Email:
alangham@sfire.com  and  (ii)  your responses to the questions contained therein
will  be  true  and  correct in all respects. In addition, you have agreed that,
concurrently  with  your execution of this letter, you will execute the attached
instrument  directed  to  Biogen  informing  Biogen  that  you  consent to being
nominated by Icahn for election as a director of Biogen and, if elected, consent
to serving as a director of Biogen. Upon being notified that we have chosen you,
we  may  forward  that  consent  and  your completed questionnaire (or summaries
thereof)  to  Biogen.

     Icahn hereby agrees that, so long as you actually serve on the Slate, Icahn
will  defend,  indemnify  and  hold  you  harmless  from and against any and all
losses,  damages, penalties, judgments, awards, liabilities, costs, expenses and
disbursements (including, without limitation, reasonable attorneys' fees, costs,
expenses  and  disbursements) incurred by you in the event that (i) you become a
party,  or  are  threatened  to  be  made  a  party,  to  any  civil,  criminal,
administrative or arbitrative action, suit or proceeding, and any appeal thereof
relating solely to your role as a nominee for director of Biogen on the Slate (a
"Proceeding")  or  (ii)  you  are  called to testify or give a deposition in any
Proceeding  (whether or not you are a party or are threatened to be made a party
to  such  Proceeding),  including,  in  each case, the advancement to you of all
reasonable  attorneys' costs and expenses incurred by you in connection with any
Proceeding.  Your  right  of indemnification hereunder shall continue (i) in the
event  that  Icahn determines to withdraw the Slate or remove you from the Slate
and  (ii)  after  the  election  has taken place but only for events which occur
prior  to  such  election  and  subsequent  to  the date hereof. Anything to the
contrary  herein  notwithstanding,  Icahn is not indemnifying you for any action
taken  by  you  or  on  your  behalf  which  occurs  prior to the date hereof or
subsequent  to  the  Annual  Meeting or such earlier time as you are no longer a
nominee  of  the  Slate  for  election to Biogen's Board of Directors or for any
actions taken by you as a director of Biogen, if you are elected. Nothing herein
shall  be  construed to provide you an indemnity: (i) in the event you are found
to  have  engaged  in  a  violation  of any provision of state or federal law in
connection  with  the  Proxy Contest unless you demonstrate that your action was
taken  in  good  faith  and  in a manner you reasonably believed to be in or not
opposed  to  the best interests of electing the Slate; or (ii) if you acted in a
manner  which  constitutes  gross negligence or willful misconduct. In the event
that  you shall make any claim for indemnification hereunder, you shall promptly
notify Icahn in the event of any third-party claims actually made against you or
known  by  you  to  be  threatened. In addition, with respect to any such claim,
Icahn  shall  be  entitled to control your defense with counsel chosen by Icahn.
Icahn  shall  not  be  responsible  for  any settlement of any claim against you
covered  by this indemnity without its prior written consent. However, Icahn may
not enter into any settlement of any such claim without your consent unless such
settlement  includes  a  release of you from any and all liability in respect of
such  claim.

     Each  of us recognizes that should you be elected to the Board of Directors
of Biogen all of your activities and decisions as a director will be governed by
applicable  law and subject to your fiduciary duty to the stockholders of Biogen
and,  as a result, that there is, and can be, no agreement between you and Icahn
which  governs  the  decisions  which  you  will  make  as a director of Biogen.



     Should  the  foregoing agree with your understanding, please so indicate in
the  space provided below, whereupon this letter will become a binding agreement
between  us.

                                          Very  truly  yours,

                                          HIGH  RIVER  LIMITED  PARTNERSHIP


                                          By:  __________________________
                                               Name:  Edward  E.  Mattner
                                               Title:  Authorized  Signatory


                                          ICAHN  PARTNERS  LP


                                          By:  __________________________
                                               Name:  Edward  E.  Mattner
                                               Title:  Authorized  Signatory


                                          ICAHN  PARTNERS  MASTER  FUND  LP


                                          By:  __________________________
                                               Name:  Edward  E.  Mattner
                                               Title:  Authorized  Signatory


                                          ICAHN  PARTNERS  MASTER  FUND  II  LP


                                          By:  __________________________
                                               Name:  Edward  E.  Mattner
                                               Title:  Authorized  Signatory


                                          ICAHN  PARTNERS  MASTER  FUND  III  LP


                                          By:  __________________________
                                               Name:  Edward  E.  Mattner
                                               Title:  Authorized  Signatory

Agreed to and Accepted as
of the date first above written:


__________________________

Name: