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UFC 290 fighter Josiah Harrell withdraws due to rare brain disease ahead of fight debut

UFC and Nevada State Athletic Commission policies required Josiah Harrell to undergo a pre-fight MRI. Scans found a previously undiagnosed affliction called moyamoya disease.

Josiah Harrell was forced to withdraw from Saturday's highly anticipated UFC 290 event.

On Friday, Harrell was removed from the event due to what the promotion initially described as a "medical issue." But several hours after Harrell's scheduled promotional debut against Jack Della Maddalena was canceled, his manager shed some new light on the fighter's medical situation.

Maurice Blanco of First Round Management revealed that Harrell had been removed after scans had discovered an abnormality during a routine pre-fight brain MRI.

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Harrell was diagnosed with moyamoya disease, which is "a rare blood vessel disorder in which the carotid artery in the skull becomes blocked or narrowed," according to the Mayo Clinic.

Blanco noted that Harrell's MRI "may have saved his life." He also mentioned that Harrell will likely undergo brain surgery in the near future.

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Harrell did not know he suffered from the disease, according to Blanco. He had been set to make his MMA debut at UFC 290.

Blanco also expressed gratitude for the UFC and the Nevada Athletic Commission's medical testing requirements. 

He noted that while Harrell had fought in three other states during his professional career, he was not required to undergo any pre-fight medical screenings.

In 2019, bantamweight Vince Murdock was removed from his scheduled debut after a pre-fight medical scan showed that he had moyamoya disease. Murdock later underwent brain surgery. He then went through a rehabilitation process and returned to the sport in 2020.

Blanco said that as of Saturday, Harrell remains on the UFC roster.

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