* |
If the form is filed by more than one reporting person, see Instruction 5(b)(v). |
** |
Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a). |
(1) |
The reported securities are owned directly by Omega Fund I, L.P. ("Omega I"). Omega I, Omega Fund GP, Ltd. ("Omega GP"), Omega Fund Management Limited ("Omega Management") and Sigma Holding Limited ("Sigma") have previously reported as ten percent owners. Sharon Rose Alvarez-Masterton ("Alvarez-Masterton") is a ten percent holder, and she is a director of each of (i) Omega GP, which is the general partner of Omega I, (ii) Omega Management, which is the sole shareholder of Omega GP and (iii) Sigma, which is the sole shareholder of Omega Management. Alvarez-Masterton disclaims beneficial ownership of the reported securities except to the extent of her pecuniary interest therein. |
(2) |
All shares reported herein reflect an issuance of Common Stock by the Issuer on June 22, 2007. |
(3) |
The reported securities are directly held by Omega Fund III, L.P. ("Omega III"). Omega Fund III GP, L.P. ("Omega III GPLP") is the general partner of Omega III. Omega Fund III G.P., Ltd. ("Omega III GPLtd") is the general partner of Omega III GPLP. Omega Management is the sole shareholder of Omega III GPLtd. Sigma is the sole shareholder of Omega Management. Alvarez-Masterton is a director of each of (i) Omega III GPLtd, (ii) Omega Management, and (iii) Sigma. Alvarez-Masterton disclaims beneficial ownership of the reported securities except to the extent of her pecuniary interest therein. |
(4) |
All shares reported herein reflect an issuance of Warrant in connection with the issuance of Common Stock on June 22, 2007. |