SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                               Schedule 13G Under
             Information Statement Pursuant to Rules 13d-1 and 13d-2
                    Under The Securities Exchange Act of 1934

                                (Amendment No.1)





                               McKesson HBOC, Inc.
-------------------------------------------------------------------------------
                                (Name Of Issuer)


                                  Common Stock
-------------------------------------------------------------------------------
                         (Title of Class of Securities)

                                    58155Q103
                         ------------------------------
                                 (Cusip Number)














                      (Continued on the following page(s))

                                Page 1 of 6 Pages





CUSIP NO. 58155Q103          13G                          Page 2 of 6 Pages
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McKesson HBOC, Inc.
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   1       NAME OF REPORTING PERSON
           S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON.
           The Chase Manhattan Bank - CMB SS # 13-4494650
           As Trustee for McKesson Master Trust Agreement SS # 13-1027923

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   2       CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*           (A)  [ ]
                                                                       (B)  [ ]

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   3       SEC USE ONLY


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   4       CITIZENSHIP OR PLACE OF ORGANIZATION
           The Chase Manhattan Bank - New York
           McKesson Master Trust - New York
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                           5      SOLE VOTING POWER

                                  0
                           -----------------------------------------------------
       NUMBER OF           6      SHARED VOTING POWER
        SHARES
     BENEFICIALLY                 Plan: 16,110,354
       OWNED BY
         EACH              -----------------------------------------------------
       REPORTING           7      SOLE DISPOSITIVE POWER
        PERSON
         WITH

                           -----------------------------------------------------
                           8      SHARED DISPOSITIVE POWER

                                  Plan: 16,110,354
--------------------------------------------------------------------------------
   9       AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

           Plan: 16,110,354
--------------------------------------------------------------------------------
   10      CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN
           SHARES*
                                                                            [ ]

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   11      PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

           Plan: 5.69%
--------------------------------------------------------------------------------
   12      TYPE OF PERSON REPORTING*

           CMB - BK
           Plan - DC
--------------------------------------------------------------------------------
                     * SEE INSTRUCTION BEFORE FILLING OUT!






Item 1(a). Name of Issuer:                         McKesson HBOC, Inc.

Item 1(b). Address of Issuer:                      1 Post Street Suite 2800
    Principal Executive Offices:                   San Francisco, CA 94104

         Principal Executive Officer:              Mr. Chris Maher, VP,
                                                   Compensation & Benefits

Item 2(a). Name of Person Filing:                  This notice is filed by The
                                                   Chase Manhattan Bank (CMB)
                                                   and McKesson HBOC Profit
                                                   Sharing Investment Plan(the
                                                   Plan) and Trust created
                                                   pursuant thereto
                                                   (collectively, the Filing
                                                   Persons)


Item 2(b). Address of Principal Business           CMB: 270 Park Avenue
                                                        New York, NY 10017
                                                   Plan: McKesson Master Trust
                                                   c/o the Chase Manhattan Bank

Item 2(c). Citizenship:                            CMB  - New York

Item 2(d). Title of Class of Securities:           Common Stock

Item 2(e). CUSIP Number:                           58155Q103






                                   Page 3 of 6






                               McKesson HBOC, Inc.

Item 3. If this statement is filed pursuant to Rules 13d-1(b), or 13d-2(b),
        check whether the person filing is a:

          (a) [   ]   Broker or dealer registered under Section 15 of the Act.

          (b) [ X ]   Bank as defined in Section 3(a)(6) of the Act.

          (c) [   ]   Insurance Company as defined in Section 3(a)(19) of the
                      Act.

          (d) [   ]   Investment Company registered under Section 8 of the
                      Investment Company Act.

          (e) [   ]   Investment Adviser registered under Section 203 of the
                      Investment Advisers Act of 1940.

          (f) [ X ]   Employee Benefit Plan, Pension Fund which is subject
                      to the provisions of the Employee Retirement Income
                      Security Act of 1974 or endowment Fund [see Section
                      240.13d-1(b)(1)(ii)(F)].

          (g) [   ]   Parent Holding Company, in accordance with Section
                      240.13d-1(b)(ii)(G).

          (h) [   ]   Group, in accordance with Section 240.13d-1(ii)(H).

Item 4.   Ownership:

          (a)     Amount Beneficially Owned:
                  As of December 31, 2000    Plan: 16,110,354

          (b)     Percent of Class:                   5.69 %

          (c)     Number of shares as to which such person has:

                  (i)   Sole power to vote or to direct the vote:

                  (ii) Shared power to vote or to direct the vote:




                                   Page 4 of 6







                           McKesson HBOC, Inc.


                  (iii)   Sole power to dispose or to direct the disposition of:


                  (iv)    Shared power to dispose or to direct the disposition
                          of:

The Plan and Trust created pursuant thereto share the power to dispose or direct
the disposition of 16,110,354 shares of Common Stock.

The 16,110,354 shares of Common Stock are held in the Trust created pursuant to
the McKesson Master Trust Agreement, dated January 1, 1988, (and as subsequently
amended) between Chase as the Master Trustee (the Master Trustee) and McKesson
HBOC, Inc. for the benefit of Participants in the McKesson HBOC Profit Sharing
Investment Plan (Trust).

Except as set forth below, the Master Trustee is obligated, under the terms of
the Trust and the terms of the Plan, to vote, tender or exchange and Common
Stock beneficially owned by the Trust as directed by Participants in the Plan
(the Participants).

For this purpose, each Participant acts in the capacity of a named Fiduciary
with respect to all shares of Common Stock as to which such Participant has the
rights of direction with respect to voting, exchange and any other rights
appurtenant to such stock.

Under the terms of the Trust, The Master Trustee will vote shares of Common
Stock allocated to the accounts of Participants in accordance with the
instructions given by such Participants. Unallocated shares of Common Stock,
together with any allocated shares for which no instructions are received
(except for certain shares of Common Stock allocated to Participants accounts
under the PAYSOP feature of the Plan (the PAYSOP Shares), are voted by the
Master Trustee in the same proportion as the shares of Common Stock for which
instructions are received.

The administrators of the Plan may cause the Master Trustee to dispose of shares
of Common Stock under certain limited circumstances

The actions of the Master Trustee under the terms of the Trust, including but
not limited to the provisions described above, are subject to the requirements
of ERISA.


Item 5.    Ownership of Five Percent or Less of a Class:
           Not applicable


Item 6.    Ownership of More than Five Percent on Behalf of Another Person:
           Not applicable

                                   Page 5 of 6







Item 7.    Identification and Classification of the Subsidiary Which Holds the
           Security Being Reported on by the Parent Holding Company:
           Not applicable.

Item 8.    Identification and Classification of Members of this Group:
           Not applicable.

Item 9.    Notice of Dissolution of Group:
           Not applicable.

Item 10.   Certification:

           By signing below, I certify that, to the best of my knowledge and
           belief, the securities referred to above were acquired in the
           ordinary course of business and were not acquired for the purpose of
           and did not have the effect of changing or influencing the control of
           the issuer of such securities and were not acquired in connection
           with or as a participant in any transaction having such purpose or
           effect.


Signature: After reasonable inquiry and to the best of my knowledge and belief,
           I certify that the information set forth in this statement is true,
           complete and correct.






Dated:  Februray 12, 2001




The Chase Manhattan Bank

/S/ Maureen Galante
-----------------------------
    Maureen Galante
    Trust Compliance Officer



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