UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A (Amendment No. 7) Under the Securities Exchange Act of 1934 Neose Technolgies, Inc ---------------------- Common Stock, no par value per share (Title of Class of Securities) ------------------------------ 640522108 --------- CUSIP Number December 31, 2004 ----------------- (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Schedule is filed: |_| Rule 13d-1(b) |X| Rule 13d-1(c) |_| Rule 13d-1(d) *The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page. The information required on the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes). Continued on following pages Page 1 of 13 Pages Exhibit Index: Page 12 SCHEDULE 13G CUSIP No. 640522108 Page 2 of 12 -------------------------------------------------------------------------------- 1 Names of Reporting Persons I.R.S. Identification Nos. of above persons (entities only) PARAMOUNT BIOCAPITAL ASSET MANAGEMENT, INC. -------------------------------------------------------------------------------- 2 Check the Appropriate Box If a Member of a Group * a. |_| b. |X| -------------------------------------------------------------------------------- 3 SEC Use Only -------------------------------------------------------------------------------- 4 Citizenship or Place of Organization DELAWARE -------------------------------------------------------------------------------- 5 Sole Voting Power Number of 0 Shares ---------------------------------------------------- Beneficially 6 Shared Voting Power Owned By 21,000 Each ---------------------------------------------------- Reporting 7 Sole Dispositive Power Person 0 With ---------------------------------------------------- 8 Shared Dispositive Power 21,000 -------------------------------------------------------------------------------- 9 Aggregate Amount Beneficially Owned by Each Reporting Person 21,000 -------------------------------------------------------------------------------- 10 Check Box If the Aggregate Amount in Row (9) Excludes Certain Shares * |_| -------------------------------------------------------------------------------- 11 Percent of Class Represented By Amount in Row (9) 0.1% -------------------------------------------------------------------------------- 12 Type of Reporting Person * CO -------------------------------------------------------------------------------- * see instructions before filling out SCHEDULE 13G CUSIP No. 640522108 Page 3 of 12 -------------------------------------------------------------------------------- 1 Names of Reporting Persons I.R.S. Identification Nos. of above persons (entities only) ARIES SELECT, LTD. -------------------------------------------------------------------------------- 2 Check the Appropriate Box If a Member of a Group * a. |_| b. |_| -------------------------------------------------------------------------------- 3 SEC Use Only -------------------------------------------------------------------------------- 4 Citizenship or Place of Organization CAYMAN ISLANDS -------------------------------------------------------------------------------- 5 Sole Voting Power Number of 0 Shares ---------------------------------------------------- Beneficially 6 Shared Voting Power Owned By 0 Each ---------------------------------------------------- Reporting 7 Sole Dispositive Power Person 0 With ---------------------------------------------------- 8 Shared Dispositive Power 0 -------------------------------------------------------------------------------- 9 Aggregate Amount Beneficially Owned by Each Reporting Person 0 -------------------------------------------------------------------------------- 10 Check Box If the Aggregate Amount in Row (9) Excludes Certain Shares * |_| -------------------------------------------------------------------------------- 11 Percent of Class Represented By Amount in Row (9) 0% -------------------------------------------------------------------------------- 12 Type of Reporting Person * CO -------------------------------------------------------------------------------- * see instructions before filling out SCHEDULE 13G CUSIP No. 640522108 Page 4 of 12 -------------------------------------------------------------------------------- 1 Names of Reporting Persons I.R.S. Identification Nos. of above persons (entities only) LINDSAY A. ROSENWALD, M.D. -------------------------------------------------------------------------------- 2 Check the Appropriate Box If a Member of a Group * a. |_| b. |X| -------------------------------------------------------------------------------- 3 SEC Use Only -------------------------------------------------------------------------------- 4 Citizenship or Place of Organization UNITED STATES -------------------------------------------------------------------------------- 5 Sole Voting Power Number of 130,326 Shares ---------------------------------------------------- Beneficially 6 Shared Voting Power Owned By 126,974 Each ---------------------------------------------------- Reporting 7 Sole Dispositive Power Person 130,326 With ---------------------------------------------------- 8 Shared Dispositive Power 126,974 -------------------------------------------------------------------------------- 9 Aggregate Amount Beneficially Owned by Each Reporting Person 257,300 -------------------------------------------------------------------------------- 10 Check Box If the Aggregate Amount in Row (9) Excludes Certain Shares * |_| -------------------------------------------------------------------------------- 11 Percent of Class Represented By Amount in Row (9) 1.0% -------------------------------------------------------------------------------- 12 Type of Reporting Person * IN -------------------------------------------------------------------------------- * see instructions before filling out SCHEDULE 13G CUSIP No. 640522108 Page 5 of 12 -------------------------------------------------------------------------------- 1 Names of Reporting Persons I.R.S. Identification Nos. of above persons (entities only) ARIES SELECT I LLC -------------------------------------------------------------------------------- 2 Check the Appropriate Box If a Member of a Group * a. |_| b. |X| -------------------------------------------------------------------------------- 3 SEC Use Only -------------------------------------------------------------------------------- 4 Citizenship or Place of Organization DELAWARE -------------------------------------------------------------------------------- 5 Sole Voting Power Number of 0 Shares ---------------------------------------------------- Beneficially 6 Shared Voting Power Owned By 0 Each ---------------------------------------------------- Reporting 7 Sole Dispositive Power Person 0 With ---------------------------------------------------- 8 Shared Dispositive Power 0 -------------------------------------------------------------------------------- 9 Aggregate Amount Beneficially Owned by Each Reporting Person 0 -------------------------------------------------------------------------------- 10 Check Box If the Aggregate Amount in Row (9) Excludes Certain Shares * |_| -------------------------------------------------------------------------------- 11 Percent of Class Represented By Amount in Row (9) 0% -------------------------------------------------------------------------------- 12 Type of Reporting Person * CO -------------------------------------------------------------------------------- * see instructions before filling out SCHEDULE 13G CUSIP No. 640522108 Page 6 of 12 -------------------------------------------------------------------------------- 1 Names of Reporting Persons I.R.S. Identification Nos. of above persons (entities only) ARIES SELECT II LLC -------------------------------------------------------------------------------- 2 Check the Appropriate Box If a Member of a Group * a. |_| b. |X| -------------------------------------------------------------------------------- 3 SEC Use Only -------------------------------------------------------------------------------- 4 Citizenship or Place of Organization DELAWARE -------------------------------------------------------------------------------- 5 Sole Voting Power Number of 0 Shares ---------------------------------------------------- Beneficially 6 Shared Voting Power Owned By 0 Each ---------------------------------------------------- Reporting 7 Sole Dispositive Power Person 0 With ---------------------------------------------------- 8 Shared Dispositive Power 0 -------------------------------------------------------------------------------- 9 Aggregate Amount Beneficially Owned by Each Reporting Person 0 -------------------------------------------------------------------------------- 10 Check Box If the Aggregate Amount in Row (9) Excludes Certain Shares * |_| -------------------------------------------------------------------------------- 11 Percent of Class Represented By Amount in Row (9) 0% -------------------------------------------------------------------------------- 12 Type of Reporting Person * CO -------------------------------------------------------------------------------- * see instructions before filling out CUSIP No. 640522108 Page 7 of 12 Item 1(a) Name of Issuer: Neose Technologies, Inc. (the "Issuer") Item 1(b) Address of the Issuer's Principal Executive Offices: 102 Whitman Road Horsham, PA 19044 Item 2(a) Name of Person Filing: This statement is filed on behalf of Paramount BioCapital Asset Management, Inc. ("Paramount BioCapital"), Aries Select, Ltd. ("Aries Select"), Aries Select I LLC ("Aries I"), Aries Select II LLC ("Aries II") and Lindsay A. Rosenwald, M.D. ("Dr. Rosenwald" and collectively, the "Reporting Persons"). Item 2(b) Address of Principal Business Office or, if None, Residence: The address of the principal business office of Paramount BioCapital, Aries I, Aries II and Dr. Rosenwald is 787 Seventh Avenue, 48th Floor, New York, New York, 10019. The address of the principal business office of Aries Select is c/o Fortis Fund Services Cayman Limited, Grand Pavilion Commercial Center, 802 West Bay Road, Grand Cayman, Cayman Islands. Item 2(c) Citizenship: 1) Paramount BioCapital is a Subchapter S corporation incorporated in Delaware; 2) Aries Select is a Cayman Islands exempted company; 3) Aries I and Aries II are Delaware limited liability companies; 4) Dr. Rosenwald is a citizen of the United States. Item 2(d) Title of Class of Securities: Common Stock (the "Shares"). Item 2(e) CUSIP Number: 640522108 Item 3. If this statement is filed pursuant to Rule 13d-1(b), or 13d-2(b) or (c), check whether the person filing is a: This Item 3 is not applicable. Item 4. Ownership: Item 4(a) Amount Beneficially Owned: CUSIP No. 640522108 Page 8 of 12 Each of the Reporting Persons may be deemed the beneficial owner of the following number of Shares: (i) Paramount BioCapital may be deemed to own 21,100 Shares, which includes 16,100 Shares owned by the Abington Biomedical Master Fund and 5,000 Shares owned by the Joseph Stevens Biotechnology Fund. (ii) Aries Select, Aries I and Aries II no longer own any Shares. (iii) Dr. Rosenwald may be deemed the beneficial owner of 257,300 Shares as follows: (a) all shares described in (i) and (ii) above; (b) 130,326 Shares owned directly by Dr. Rosenwald; and (c) 105,974 shares owned by Dr. Rosenwald's wife and children Item 4(b) Percent of Class: Please see Item 11 of each cover page. Item 4(c) Number of shares as to which such person has: (i) Sole power to vote or direct the vote: Please see Item 5 of each cover page (ii) Shared power to vote or to direct the vote Please see Item 6 of each cover page (iii) Sole power to dispose or to direct the disposition of Please see Item 7 of each cover page (iv) Shared power to dispose or to direct the disposition of Please see Item 8 of each cover page Item 5. Ownership of Five Percent or Less of a Class: If this statement is being filed to report the fact that the Reporting Person has ceased to be the beneficial owner of more than five percent of a class of securities of the Issuer, check the following box. |X| During 2004, the Reporting Persons, individually and collectively, ceased to be a beneficial owner of more than 5% of any class of securities of the Issuer. Item 6. Ownership of More than Five Percent on Behalf of Another Person: This Item 6 is not applicable. Item 7. Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company: This Item 7 is not applicable. Item 8. Identification and Classification of Members of the Group: This Item 8 is not applicable. Item 9. Notice of Dissolution of Group: CUSIP No. 640522108 Page 9 of 12 This Item 9 is not applicable. Item 10. Certification: By signing below each of the Reporting Persons certifies that, to the best of such person's knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the Issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect. Page 10 of 12 SIGNATURES After reasonable inquiry and to the best of my knowledge and belief, the undersigned certifies that the information set forth in this statement is true, complete and correct, as of this February 10, 2005. LINDSAY A. ROSENWALD, M.D. PARAMOUNT BIOCAPITAL ASSET MANAGEMENT, INC. By /s/ LINDSAY A. ROSENWALD By: /s/ LINDSAY A. ROSENWALD --------------------------- ----------------------------- Name: Lindsay A. Rosenwald, M.D. Title: Chairman ARIES SELECT, LTD. By: Paramount BioCapital Asset Management, Inc. Its: Investment Manager By: /s/ LINDSAY A. ROSENWALD ---------------------------- Name: Lindsay A. Rosenwald, M.D. Title: Chairman ARIES SELECT I LLC By: Paramount BioCapital Asset Management, Inc. Its Managing Manager By: /s/ LINDSAY A. ROSENWALD ---------------------------- Name: Lindsay A. Rosenwald, M.D. Title: Chairman ARIES SELECT II LLC By: Paramount BioCapital Asset Management, Inc. Its Managing Manager By: /s/ LINDSAY A. ROSENWALD ---------------------------- Name: Lindsay A. Rosenwald, M.D. Title: Chairman CUSIP No. 640522108 Page 11 of 12 EXHIBIT INDEX Page No. -------- A. Joint Filing Agreement, dated as of February 10, 2005, by and among Paramount BioCapital Asset Management, Inc., Aries Select, Ltd., Aries Select I LLC, Aries Select II, LLC, and Lindsay A. Rosenwald, M.D................... 12 CUSIP No. 640522108 Page 12 of 12 EXHIBIT A JOINT FILING AGREEMENT The undersigned hereby agree that the statement on Schedule 13G with respect to the Common Stock of Neose Technologies, Inc. dated as of February 10, 2005, is, and any amendments thereto (including amendments on Schedule 13D) signed by each of the undersigned shall be, filed on behalf of each of us pursuant to and in accordance with the provisions of Rule 13d-1(k) under the Securities Exchange Act of 1934. LINDSAY A. ROSENWALD, M.D. PARAMOUNT BIOCAPITAL ASSET MANAGEMENT, INC. By /s/ LINDSAY A. ROSENWALD By: /s/ LINDSAY A. ROSENWALD --------------------------- ----------------------------- Name: Lindsay A. Rosenwald, M.D. Title: Chairman ARIES SELECT, LTD. By: Paramount BioCapital Asset Management, Inc. Its: Investment Manager By: /s/ LINDSAY A. ROSENWALD ---------------------------- Name: Lindsay A. Rosenwald, M.D. Title: Chairman ARIES SELECT I LLC By: Paramount BioCapital Asset Management, Inc. Its Managing Manager By: /s/ LINDSAY A. ROSENWALD ---------------------------- Name: Lindsay A. Rosenwald, M.D. Title: Chairman ARIES SELECT II LLC By: Paramount BioCapital Asset Management, Inc. Its Managing Manager By: /s/ LINDSAY A. ROSENWALD ---------------------------- Name: Lindsay A. Rosenwald, M.D. Title: Chairman