SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549


                                  SCHEDULE 13G


             Information Statement Pursuant to Rules 13d-1 and 13d-2
                    Under the Securities Exchange Act of 1934
                               (Amendment No. 1)*


                                  Nanogen, Inc.
                                (Name of Issuer)


                                  Common Stock
                         (Title of Class of Securities)


                                    630075109
                                 (CUSIP Number)


                                January 29, 2004
             (Date of Event Which Requires Filing of This Statement)



Check the appropriate box to designate the rule pursuant to which this Schedule
is filed:

         [_]      Rule 13d-1(b)
         [X]      Rule 13d-1(c)
         [_]      Rule 13d-1(d)

*The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities, and
for any subsequent amendment containing information which would alter
disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the Securities Exchange Act of
1934 ("Act") or otherwise subject to the liabilities of that section of the Act
but shall be subject to all other provisions of the Act (however, see the
Notes).



                                                                               2


CUSIP No. 630075109

1.       Name of Reporting Person:

         Langley Partners, L.P.

2.       Check the Appropriate Box if a Member of a Group:

         (a)      [_]

         (b)      [X]

3.       SEC Use Only

4.       Citizenship or Place of Organization: Delaware

                        5.      Sole Voting Power: -0-
Number of
Shares
Beneficially            6.      Shared Voting Power: 813,864 (see Item 4)
Owned By
Each
Reporting               7.      Sole Dispositive Power:  -0-
Person
With
                        8.      Shared Dispositive Power: 813,864 (see Item 4)

9.       Aggregate Amount Beneficially Owned by Each Reporting Person:

         813,864

10.      Check Box if the Aggregate Amount in Row (9) Excludes Certain Shares:

         [_]

11.      Percent of Class Represented by Amount in Row (9): 3.2%

12.      Type of Reporting Person: PN




                                                                               3


CUSIP No. 630075109

1.       Name of Reporting Person:

         Langley Management, LLC

2.       Check the Appropriate Box if a Member of a Group:

         (a)      [_]

         (b)      [X]

3.       SEC Use Only

4.       Citizenship or Place of Organization: Delaware

                        5.      Sole Voting Power: -0-
Number of
Shares
Beneficially            6.      Shared Voting Power: 813,864 (see Item 4)
Owned By
Each
Reporting               7.      Sole Dispositive Power: -0-
Person
With
                        8.      Shared Dispositive Power: 813,864 (see Item 4)

9.       Aggregate Amount Beneficially Owned by Each Reporting Person:

         813,864

10.      Check Box if the Aggregate Amount in Row (9) Excludes Certain Shares:

         [_]

11.      Percent of Class Represented by Amount in Row (9): 3.2%

12.      Type of Reporting Person: OO




                                                                               4


CUSIP No. 630075109

1.       Name of Reporting Person:

         Langley Capital, LLC

2.       Check the Appropriate Box if a Member of a Group:

         (a)      [_]

         (b)      [X]

3.       SEC Use Only

4.       Citizenship or Place of Organization: Delaware

                        5.      Sole Voting Power: -0-
Number of
Shares
Beneficially            6.      Shared Voting Power:  813,864 (see Item 4)
Owned By
Each
Reporting               7.      Sole Dispositive Power:  -0-
Person
With
                        8.      Shared Dispositive Power: 813,864 (see Item 4)

9.       Aggregate Amount Beneficially Owned by Each Reporting Person:

         813,864

10.      Check Box if the Aggregate Amount in Row (9) Excludes Certain Shares:

         [_]

11.      Percent of Class Represented by Amount in Row (9): 3.2%

12.      Type of Reporting Person: OO



                                                                               5


CUSIP No. 630075109

1.       Name of Reporting Person:

         Jeffrey Thorp

2.       Check the Appropriate Box if a Member of a Group:

         (a)      [_]

         (b)      [X]

3.       SEC Use Only

4.       Citizenship or Place of Organization: United States

                        5.      Sole Voting Power: -0-
Number of
Shares
Beneficially            6.      Shared Voting Power:  813,864 (see Item 4)
Owned By
Each
Reporting               7.      Sole Dispositive Power:  -0-
Person
With
                        8.      Shared Dispositive Power: 813,864 (see Item 4)

9.       Aggregate Amount Beneficially Owned by Each Reporting Person:

         813,864

10.      Check Box if the Aggregate Amount in Row (9) Excludes Certain Shares:

         [_]

11.      Percent of Class Represented by Amount in Row (9): 3.2%

12.      Type of Reporting Person: IN



                                                                               6


                  This Amendment No. 1 to Schedule 13G is filed by the
undersigned to amend and restate in its entirety the Schedule 13G, dated as of
September 24, 2003, with respect to the shares of Common Stock, par value $0.001
per share, of Nanogen, Inc.

Item 1(a).        Name of Issuer:

                  Nanogen, Inc. (the "Company").

Item 1(b).        Address of Issuer's Principal Executive Offices:

                  10398 Pacific Center Court
                  San Diego, CA 92121

Item 2(a).        Name of Persons Filing:

                  (i) Langley Partners, L.P. ("Langley L.P."), (ii) Langley
                  Management, LLC, (iii) Langley Capital, LLC and (iv) Jeffrey
                  Thorp ("Thorp", together with Langley L.P., Langley
                  Management, LLC and Langley Capital, LLC, the "Reporting
                  Persons").

Item 2(b).        Address of Principal Business Office:

                  For each Reporting Person:

                  535 Madison Avenue
                  7th Floor
                  New York, NY 10022.

Item 2(c).        Citizenship:

                  See row 4 of each Reporting Persons' cover page.

Item 2(d).        Title of Class of Securities:

                  Common Stock, $0.001 par value per share, of the Company

Item 2(e).        CUSIP Number:

                  630075109

Item 3.           Not applicable.

Item 4.           Ownership.

                  For each Reporting Person:

                  (a)      Amount beneficially owned:



                                                                               7


                           813,864 shares of Common Stock as follows: (i)
                           626,364 shares of Common Stock issuable to Langley
                           L.P. upon exercise of the six month warrants (the
                           "Six Month Warrants") to purchase Common Stock of the
                           Company expiring on March 19, 2004 and (ii) 187,500
                           shares of Common Stock issuable to Langley L.P. upon
                           exercise of the one year warrants (the "One Year
                           Warrants") to purchase Common Stock of the Company
                           expiring on September 19, 2004.

                           Langley Capital, LLC is the general partner of
                           Langley L.P. Thorp is the sole member and manager of
                           Langley Capital, LLC. Langley Management, LLC is the
                           investment manager of Langley L.P. Thorp holds a
                           99.9% membership interest in Langley Management, LLC
                           and is the sole manager thereof. As a result, each of
                           Langley Management, LLC, Langley Capital, LLC and
                           Thorp are considered to share the power to vote or
                           direct the vote of, and the power to dispose or
                           direct the disposition of, the shares of Common Stock
                           directly beneficially owned by Langley L.P. This
                           statement on Schedule 13G shall not be construed as
                           an admission that any of the Reporting Persons (other
                           than Langley L.P.) is the beneficial owner of the
                           Common Stock covered by this statement.

                  (b)      Percent of class:

                           3.2% of the total outstanding shares of Common Stock.
                           This percentage is based upon 25,193,874 shares of
                           Common Stock issued and outstanding, which number is
                           calculated by adding (i) 24,380,010 (the number of
                           shares of Common Stock reported on the Form 10-Q for
                           the period ended September 30, 2003), (ii) 626,364
                           (the number of shares of Common Stock issuable to
                           Langley L.P. upon exercise of the Six Month Warrants)
                           and (iii) 187,500 (the number of shares of Common
                           Stock issuable to Langley L.P. upon exercise of the
                           One Year Warrants).

                  (c)      Number of shares to which each Reporting Person has:

                           (i)      Sole power to vote or direct the vote: -0-

                           (ii)     Shared power to vote or direct the vote:
                                    813,864

                           (iii)    Sole power to dispose or to direct the
                                    disposition of: -0-

                           (iv)     Shared power to dispose of or direct the
                                    disposition of: 813,864

Item 5.           Ownership of Five Percent or Less of a Class.

                  If this statement is being filed to report the fact that as of
                  the date hereof the reporting person has ceased to be the
                  beneficial owner of more than five percent of the class of
                  securities check the following [X].

Item 6.           Ownership of More than Five Percent on Behalf of Another
                  Person.

                  Not Applicable.



                                                                               8


Item 7.           Identification and Classification of the Subsidiary Which
                  Acquired the Security Being Reported By the Parent Holding
                  Company.

                  Not Applicable.

Item 8.           Identification and Classification of Members of the Group.

                  Not Applicable.

Item 9.           Notice of Dissolution of a Group.

                  Not Applicable.

Item 10.          Certification.

                  By signing below I certify that, to the best of my knowledge
                  and belief, the securities referred to above were not acquired
                  and are not held for the purpose of or with the effect of
                  changing or influencing the control of the issuer of the
                  securities and were not acquired and are not held in
                  connection with or as a participant in any transaction having
                  that purpose or effect.



                                                                               9


                                    SIGNATURE

         After reasonable inquiry and to the best of my knowledge and belief, I
certify that the information set forth in this statement is true, complete and
correct.

Dated:   January 29, 2004

                                   LANGLEY PARTNERS, L.P.

                                   By:  LANGLEY CAPITAL, LLC,
                                        as General Partner

                                   By:  /s/ Jeffrey Thorp
                                        ---------------------------------------
                                        Jeffrey Thorp, Manager



                                   LANGLEY MANAGEMENT, LLC

                                   By:  /s/ Jeffrey Thorp
                                        ---------------------------------------
                                        Jeffrey Thorp, Manager



                                   LANGLEY CAPITAL, LLC

                                   By:  /s/ Jeffrey Thorp
                                        ---------------------------------------
                                        Jeffrey Thorp, Manager



                                   /s/ Jeffrey Thorp
                                   --------------------------------------------
                                   Jeffrey Thorp