Washington, D.C. 20549

                                    FORM 8-K

                Current Report Pursuant to Section 13 or 15(d) of
                       the Securities Exchange Act of 1934

                Date of Report (Date of earliest event reported):
                                February 26, 2001

                               McKESSON HBOC, Inc.
             (Exact name of registrant as specified in its charter)

         Delaware                  1-13252               94-3207296
        (State or other       (Commission File        (I.R.S. Employer
        jurisdiction of            Number)             Identification
        Incorporation)                                     Number)

        McKesson Plaza
        One Post Street
        San Francisco, California                         94104
        (Address of principal executive offices)        (Zip Code)

                                 (415) 983-8300
              (Registrant's telephone number, including area code)


Item 5.   Other Events.

On February 26, 2001, Registrant McKesson HBOC, Inc., (the "Company") announced
that John H. Hammergren currently co-CEO of the Company and CEO of its McKesson
HBOC business unit, will become President and CEO of McKesson HBOC, Inc.
effective April 1, 2001. The Company further announced that its iMcKesson
business unit will be restructured by moving the physician offerings and
transaction hub into its Information Technology Business. Its medical management
business will become a standalone unit financially reported within the Company's
Supply Management Business. David Mahoney, currently co-CEO of the Company and
CEO of iMcKesson, will leave the Company and resign from its Board of Directors.
The text of the Company's press release regarding this announcement is set forth
in Exhibit 99.1 to this Current Report on Form 8-K.

Item 7. Financial Statements, Pro Forma Financial
        Information and Exhibits.

          (c)  Exhibits

                  99.1    Press Release issued by McKesson HBOC, Inc. on
                          February 26, 2001



Pursuant to the requirements of the Securities Exchange Act of 1934, the
Registrant has duly caused this report to be signed on its behalf by the
undersigned thereunto duly authorized.

                                        McKesson HBOC, Inc.

Dated: February 26, 2001
                                        By:  /s/ Ivan D. Meyerson.
                                        Name:  Ivan D. Meyerson
                                        Title: Senior Vice President, General
                                               Counsel and Secretary


                             EXHIBIT INDEX

   No.                     Title
-------     ---------------------------------------

  99.1      Press Release issued by McKesson HBOC, Inc. on February 26, 2001.